Protein: KRT85
Keratin, type II cuticular Hb5 (Hair keratin K2.12) (Keratin-85) (K85) (Type II hair keratin Hb5) (Type-II keratin Kb25)

Gene: KRT85
Organism: Homo sapiens
Interactions: 70
UniProt ID: P78386

Gene Ontology (top 5):
GO:0005198 - structural molecule activity
GO:0005615 - extracellular space
GO:0005829 - cytosol
GO:0008544 - epidermis development
GO:0030280 - structural constituent of skin epidermis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

300642

KRT37
Keratin, type I cuticular Ha7

2

20

High-throughput

0.794

High

300338

KRT34
Keratin, type I cuticular Ha4

2

20

High-throughput

0.783

High

300563

KRT36
Keratin, type I cuticular Ha6

2

20

High-throughput

0.783

High

300744

KRT38
Keratin, type I cuticular Ha8

2

20

High-throughput

0.783

High

475560

K1C19
Keratin, type I cytoskeletal 19

2

20

High-throughput

0.783

High

476295

K1C16
Keratin, type I cytoskeletal 16

2

20

High-throughput

0.783

High

618020

K1C15
Keratin, type I cytoskeletal 15

2

20

High-throughput

0.783

High

1007516

KT33B
Keratin, type I cuticular Ha3-II

2

20

High-throughput

0.783

High

1007517

K1H1
Keratin, type I cuticular Ha1

2

20

High-throughput

0.783

High

1007523

K1C40
Keratin, type I cytoskeletal 40

2

20

High-throughput

0.783

High

1007524

K1C39
Keratin, type I cytoskeletal 39

2

20

High-throughput

0.783

High

1007527

K1C27
Keratin, type I cytoskeletal 27

2

20

High-throughput

0.783

High

1007528

K1C26
Keratin, type I cytoskeletal 26

2

20

High-throughput

0.783

High

1007529

K1C25
Keratin, type I cytoskeletal 25

2

20

High-throughput

0.783

High

1007534

KRT35
Keratin, type I cuticular Ha5

2

20

High-throughput

0.783

High

385084

K1C14
Keratin, type I cytoskeletal 14

1

20

High-throughput

0.621

High

566256

K1C13
Keratin, type I cytoskeletal 13

1

20

High-throughput

0.621

High

1007540

HPLN2
Hyaluronan and proteoglycan link protein 2

2

1

High-throughput

0.606

High

1007548

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

2

1

High-throughput

0.606

High

1007552

GLCNE
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

2

2

High-throughput

0.606

High

70174

CRTP1
Cysteine-rich tail protein 1

2

3

High-throughput

0.553

High

733121

OTX1
Homeobox protein OTX1

2

5

High-throughput

0.553

High

1007510

CREB5
Cyclic AMP-responsive element-binding protein 5

2

4

High-throughput

0.553

High

1007518

KLH38
Kelch-like protein 38

2

1

High-throughput

0.553

High

1007522

LHX8
LIM/homeobox protein Lhx8

2

4

High-throughput

0.553

High

1007530

ZN655
Zinc finger protein 655

2

3

High-throughput

0.553

High

563611

CFTR
Cystic fibrosis transmembrane conductance regulator

1

16

High-throughput

0.536

High

828198

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

7

High-throughput

0.536

High

1007509

OTUD4
OTU domain-containing protein 4

1

10

High-throughput

0.536

High

1007513

CUL3
Cullin-3

1

20

High-throughput

0.536

High

1007515

CUL4B
Cullin-4B

1

20

High-throughput

0.536

High

1007520

USPL1
SUMO-specific isopeptidase USPL1

1

1

High-throughput

0.536

High

1007538

LST8
Target of rapamycin complex subunit LST8

1

5

High-throughput

0.536

High

1007553

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

8

High-throughput

0.536

High

719209

MPIP2
M-phase inducer phosphatase 2

1

1

High-throughput

0.515

High

966188

1433G
14-3-3 protein gamma

1

13

High-throughput

0.515

High

1007511

CDC20
Cell division cycle protein 20 homolog

1

9

High-throughput

0.515

High

1007535

DLG3
Disks large homolog 3

1

4

High-throughput

0.515

High

839741

EPS15
Epidermal growth factor receptor substrate 15

1

13

High-throughput

0.479

High

986334

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

5

High-throughput

0.479

High

987536

GRB2
Growth factor receptor-bound protein 2

1

18

High-throughput

0.479

High

1007512

IKZF1
DNA-binding protein Ikaros

1

3

High-throughput

0.479

High

1007531

NHLC2
NHL repeat-containing protein 2

1

5

High-throughput

0.479

High

1007541

ATG10
Ubiquitin-like-conjugating enzyme ATG10

1

1

High-throughput

0.479

High

1007543

MYO10
Unconventional myosin-X

1

3

Small-scale

0.479

High

1007544

ANLN
Anillin

1

9

High-throughput

0.479

High

1007546

ATG3
Ubiquitin-like-conjugating enzyme ATG3

1

1

High-throughput

0.479

High

1007551

IKZF3
Zinc finger protein Aiolos

1

2

High-throughput

0.479

High

1007525

TWF2
Twinfilin-2

1

2

High-throughput

0.470

High

1007537

PKHB2
Pleckstrin homology domain-containing family B member 2

1

1

High-throughput

0.470

High

1007547

LYAR
Cell growth-regulating nucleolar protein

1

2

High-throughput

0.470

High

327938

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

20

High-throughput

0.445

High

952094

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

20

High-throughput

0.445

High

1007508

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

6

High-throughput

0.445

High

1007521

A16L1
Autophagy-related protein 16-1

1

7

High-throughput

0.445

High

1007536

RAB24
Ras-related protein Rab-24

1

4

High-throughput

0.445

High

612970

EGR1
Early growth response protein 1

1

3

High-throughput

0.437

High

914241

EFNA4
Ephrin-A4

1

20

High-throughput

0.437

High

1007514

CUL4A
Cullin-4A

1

20

High-throughput

0.437

High

1007519

RC3H1
Roquin-1

1

5

High-throughput

0.437

High

1007526

PRP8
Pre-mRNA-processing-splicing factor 8

1

7

High-throughput

0.437

High

1007532

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

7

High-throughput

0.437

High

1007539

DDX24
ATP-dependent RNA helicase DDX24

1

16

High-throughput

0.437

High

1007542

RC3H2
Roquin-2

1

10

High-throughput

0.437

High

1007549

CDK12
Cyclin-dependent kinase 12

1

4

High-throughput

0.437

High

1007550

XPO7
Exportin-7

1

5

High-throughput

0.437

High

47871

A0AUL9
ATG2A protein

1

2

High-throughput

0.407

High

1007533

ESR2
Estrogen receptor beta

1

12

High-throughput

0.407

High

1007545

TLR9
Toll-like receptor 9

1

2

High-throughput

0.348

High

348854

CLIC3
Chloride intracellular channel protein 3

2

0

High-throughput

0.316

High


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Last updated: 11Aug2025