HitPredict

Interactor 1: MED10 (Q9BTT4)
Mediator of RNA polymerase II transcription subunit 10 (Mediator complex subunit 10) (Transformation-related gene 17 protein) (TRG-17) (Transformation-related gene 20 protein) (TRG-20)
Gene: MED10

Interactor 2: MED20 (Q9H944)
Mediator of RNA polymerase II transcription subunit 20 (Mediator complex subunit 20) (TRF-proximal protein homolog) (hTRFP)
Gene: MED20

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.755

The method score is based on:

Property Details
Experiments 25281560, 24981860, 33961781, 35271311, 15175163, 14576168, 15989967, 10882111, 17404243
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016592 - mediator complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
GO:0051123 - RNA polymerase II preinitiation complex assembly
and 2 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 135
Hs

1 212
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024