Interactor 1: MED10 (Q9BTT4)
Mediator of RNA polymerase II transcription subunit 10 (Mediator complex subunit 10) (Transformation-related gene 17 protein) (TRG-17) (Transformation-related gene 20 protein) (TRG-20)
Gene: MED10

Interactor 2: MED17 (Q9NVC6)
Mediator of RNA polymerase II transcription subunit 17 (Activator-recruited cofactor 77 kDa component) (ARC77) (Cofactor required for Sp1 transcriptional activation subunit 6) (CRSP complex subunit 6) (Mediator complex subunit 17) (Thyroid hormone receptor-associated protein complex 80 kDa component) (Trap80) (Transcriptional coactivator CRSP77) (Vitamin D3 receptor-interacting protein complex 80 kDa component) (DRIP80)
Gene: MED17

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.760

The method score is based on:

Property Details
Experiments 24981860, 33961781, 35271311, 15175163, 14638676, 14576168, 12584197, 15989967, 10882111, 12149480, 17404243
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000151 - ubiquitin ligase complex
GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016592 - mediator complex
and 7 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 135
Hs

1 651
+ Dm

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Last updated: 15 Jul 2024