Protein: MAD2
Mitotic spindle checkpoint component MAD2 (Mitotic MAD2 protein)

Gene: MAD2
Organism: Saccharomyces cerevisiae S288C
Interactions: 48
UniProt ID: P40958

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0007094 - mitotic spindle assembly checkpoint signaling
GO:0033597 - mitotic checkpoint complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

829775

MAD1
Spindle assembly checkpoint component MAD1

8

1

Small-scale

0.976

High

829799

MAD2
Mitotic spindle checkpoint component MAD2

5

5

Small-scale

0.907

High

686916

BUB3
Spindle assembly checkpoint protein BUB3

3

3

Small-scale

0.847

High

684626

CDC20
APC/C activator protein CDC20

15

8

Small-scale

0.763

High

829801

MAD3
Spindle assembly checkpoint component MAD3

4

7

Small-scale

0.683

High

820274

WRIP1
DNA-dependent ATPase MGS1

1

2

High-throughput

0.656

High

829800

BUB1
Spindle assembly checkpoint serine/threonine-protein kinase BUB1

3

8

Small-scale

0.646

High

829810

RRB1
Ribosome assembly protein RRB1

1

2

High-throughput

0.618

High

616431

SEC18
Vesicular-fusion protein SEC18

1

1

High-throughput

0.587

High

367767

ENO1
Enolase 1

1

1

High-throughput

0.536

High

365641

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.513

High

439358

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.513

High

558762

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.513

High

652886

TRX2
Thioredoxin-2

1

0

High-throughput

0.513

High

701709

URA7
CTP synthase 1

1

0

High-throughput

0.513

High

829813

YO283
Broad-specificity phosphatase YOR283W

1

0

High-throughput

0.513

High

367987

ENO2
Enolase 2

1

1

High-throughput

0.489

High

645581

MSN1
Protein MSN1

1

0

High-throughput

0.486

High

805377

DNPEP
Aspartyl aminopeptidase 4

1

0

High-throughput

0.486

High

825132

POG1
Transcriptional activator POG1

1

0

High-throughput

0.486

High

829809

EBS1
Nonsense-mediated mRNA decay factor EBS1

1

0

High-throughput

0.486

High

829815

AHA1
Hsp90 co-chaperone AHA1

1

0

High-throughput

0.486

High

746366

RAEP
Rab proteins geranylgeranyltransferase component A

1

0

Small-scale

0.480

High

734520

MSB2
Signaling mucin MSB2

1

4

High-throughput

0.464

High

829806

UFD2
E4 ubiquitin-protein ligase UFD2

1

0

High-throughput

0.460

High

829814

SCM3
Protein SCM3

1

0

High-throughput

0.460

High

736793

AROG
Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited

1

0

Small-scale

0.458

High

829811

ZWINT
Outer kinetochore KNL1 complex subunit KRE28

1

0

Small-scale

0.458

High

829807

H3
Histone H3

1

1

Small-scale

0.457

High

545207

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

741760

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

829802

KEL2
Kelch repeat-containing protein 2

1

2

High-throughput

0.439

High

829805

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.438

High

801688

GLO3
ADP-ribosylation factor GTPase-activating protein GLO3

1

3

High-throughput

0.417

High

486778

CDC16
Anaphase-promoting complex subunit CDC16

1

8

Small-scale

0.408

High

829808

PDR12
ATP-dependent permease PDR12

1

0

High-throughput

0.282

High

829816

YB296
Uncharacterized protein YBR296C-A

1

0

High-throughput

0.282

High

829812

AP1G1
AP-1 complex subunit gamma-1

1

0

High-throughput

0.279

Low

733544

MED16
Mediator of RNA polymerase II transcription subunit 16

1

0

High-throughput

0.265

Low

817797

NU157
Nucleoporin NUP157

1

0

High-throughput

0.265

Low

829803

SAP4
SIT4-associating protein SAP4

1

0

High-throughput

0.265

Low

376310

YPT1
GTP-binding protein YPT1

1

0

Small-scale

0.261

Low

628320

PGTB2
Geranylgeranyl transferase type-2 subunit beta

1

0

Small-scale

0.261

Low

780030

EAP1
Protein EAP1

1

0

High-throughput

0.251

Low

812821

YJU6
Putative transcriptional regulatory protein YJL206C

1

0

High-throughput

0.251

Low

829804

YG5Q
Uncharacterized protein YGR273C

1

0

High-throughput

0.251

Low

707349

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025