HitPredict

Interactor 1: CP250 (Q9BV73)
Centrosome-associated protein CEP250 (250 kDa centrosomal protein) (Cep250) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Centrosomal protein 2)
Gene: CEP250

Interactor 2: PKHA5 (Q9HAU0)
Pleckstrin homology domain-containing family A member 5 (PH domain-containing family A member 5) (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2)
Gene: PLEKHA5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	20936779
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 2442 Hs			1 1116
+	Hs
		1068669 PLEC_HUMAN (3-1489): 1.72e-44: 181: 13.02		PKHA5_HUMAN (1-1116): 0: 609: 100.00
+	Hs
		1153312 MY18A_HUMAN (1737-2312): 8.46e-11: 70.1: 21.19		PKHA7_HUMAN (2-1059): 8.31e-125: 412: 27.32
+	Hs
		148925 CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55		MAGI3_HUMAN (1-1116): 3.96e-94: 331: 9.76
+	Hs
		725200 MYH10_HUMAN (1424-2376): 3.63e-37: 157: 13.43		RHG24_HUMAN (171-755): 5.66e-59: 219: 13.12
+	Hs
		1068666 PLEC_HUMAN (3-1489): 1.72e-44: 181: 13.02		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		149443 CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55		PKHA6_HUMAN (109-1116): 8.74e-73: 264: 28.52
+	Hs
		725245 MYH10_HUMAN (1424-2376): 3.63e-37: 157: 13.43		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		728515 MYH11_HUMAN (1406-2417): 3.68e-37: 157: 14.71		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		502926 MYH3_HUMAN (2-844): 3.25e-33: 143: 11.40		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		1059270 GOGB1_HUMAN (1634-2442): 3.53e-19: 97.7: 11.58		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		149188 CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55		MAGI1_HUMAN (1-1111): 1.6e-43: 175: 9.66
+	Hs
		1167392 MY18A_HUMAN (1737-2312): 8.46e-11: 70.1: 21.19		MPRIP_HUMAN (95-395): 8.25e-38: 155: 13.86
+	Hs
		1268094 MY18A_HUMAN (1737-2312): 8.46e-11: 70.1: 21.19		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		148966 CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55		MPRIP_HUMAN (95-395): 8.25e-38: 155: 13.86
+	Hs
		149286 CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85