HitPredict

Interactor 1: TRI62 (Q9BVG3)
E3 ubiquitin-protein ligase TRIM62 (EC 2.3.2.27) (Tripartite motif-containing protein 62)
Gene: TRIM62

Interactor 2: CARD9 (Q9H257)
Caspase recruitment domain-containing protein 9 (hCARD9)
Gene: CARD9

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.708

The method score is based on:

Property Details
Experiments 26488816, 29073062, 27779380, 33093067
Identification Methods affinity chromatography technology, pull down, fluorescent resonance energy transfer, enzymatic study, unspecified method
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0051092 - positive regulation of NF-kappaB transcription factor activity
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 475
Hs

1 536
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024