HitPredict

Interactor 1: IMA4 (O00505)
Importin subunit alpha-4 (Importin alpha Q2) (Qip2) (Karyopherin subunit alpha-3) (SRP1-gamma)
Gene: KPNA3

Interactor 2: MECP2 (P51608)
Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2)
Gene: MECP2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	28514442, 24981860, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 521 Hs			1 486
+	Hs
		134855 IMA3_HUMAN (1-521): 1.68e-160: 468: 85.80		MECP2_HUMAN (1-486): 5.16e-113: 344: 100.00
+	Hs
		134818 IMA3_HUMAN (1-521): 1.68e-160: 468: 85.80		MBD3_HUMAN (93-249): 3.06e-43: 156: 26.88
+	Hs
		328516 IMA1_HUMAN (3-521): 1.35e-143: 425: 48.49		MBD3_HUMAN (93-249): 3.06e-43: 156: 26.88
+	Hs
		328517 IMA5_HUMAN (5-520): 3.45e-133: 398: 45.52		MBD3_HUMAN (93-249): 3.06e-43: 156: 26.88
+	Hs
		853742 IMA5_HUMAN (5-520): 3.45e-133: 398: 45.52		MBD2_HUMAN (75-249): 3.32e-38: 146: 28.65
+	Hs
		168647 IMA6_HUMAN (1-520): 1.1e-135: 405: 46.65		NIPBL_HUMAN (72-455): 1.96e-09: 62.4: 14.06
+	Hs
		853625 IMA5_HUMAN (5-520): 3.45e-133: 398: 45.52		NIPBL_HUMAN (72-455): 1.96e-09: 62.4: 14.06