HitPredict

Interactor 1: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Interactor 2: SMC3 (Q9UQE7)
Structural maintenance of chromosomes protein 3 (SMC protein 3) (SMC-3) (Basement membrane-associated chondroitin proteoglycan) (Bamacan) (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP)
Gene: SMC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37071664
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005654 - nucleoplasm GO:0006281 - DNA repair
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1834 Hs			1 1217
+	Hs
		1130098 SLX4_HUMAN (1-1834): 0: 1473: 100.00		SMC1A_HUMAN (2-1211): 1.12e-80: 291: 16.52
+	Hs
		854391 KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20		SMC3_HUMAN (1-1217): 1.79e-122: 410: 100.00
+	Hs
		854058 KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20		SMC1A_HUMAN (2-1211): 1.12e-80: 291: 16.52
+	Hs
		1129589 MDC1_HUMAN (757-1462): 4.4e-17: 90.6: 10.56		SMC1A_HUMAN (2-1211): 1.12e-80: 291: 16.52
+	Hs
		1178730 MGAL_HUMAN (917-1527): 1.44e-18: 95.5: 12.11		SMC4_HUMAN (1-1206): 2.28e-77: 281: 16.77
+	Hs
		861309 MAP1B_HUMAN (819-1706): 3.35e-10: 67.8: 10.90		SMC4_HUMAN (1-1206): 2.28e-77: 281: 16.77