Interactor 1: LGR4 (Q9BXB1)
Leucine-rich repeat-containing G-protein coupled receptor 4 (G-protein coupled receptor 48)
Gene: LGR4

Interactor 2: ZNRF3 (Q9ULT6)
E3 ubiquitin-protein ligase ZNRF3 (EC 2.3.2.27) (RING finger protein 203) (RING-type E3 ubiquitin transferase ZNRF3) (Zinc/RING finger protein 3)
Gene: ZNRF3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.915

The method score is based on:

Property Details
Experiments 33262293, 33786993, 22575959, 24165923, 24639526
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_8~ZNRF_3_ecto
Common GO terms GO:0005886 - plasma membrane
GO:0016055 - Wnt signaling pathway
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 951
Hs

1 936
+ Hs
+ Hs
+ Hs
+ Zm

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Last updated: 15 Jul 2024