Protein: PIM1
Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)

Gene: PIM1
Organism: Homo sapiens
Interactions: 78
UniProt ID: P11309

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

507541

MARK3
MAP/microtubule affinity-regulating kinase 3

5

16

Small-scale

0.933

High

337841

EGFR
Epidermal growth factor receptor

3

17

High-throughput

0.843

High

507537

PIM1
Serine/threonine-protein kinase pim-1

2

18

Small-scale

0.778

High

431471

HS90A
Heat shock protein HSP 90-alpha

2

20

Small-scale

0.754

High

507592

ZBTB1
Zinc finger and BTB domain-containing protein 1

1

2

High-throughput

0.740

High

507538

KPCA
Protein kinase C alpha type

1

18

Small-scale

0.724

High

507543

MPIP1
M-phase inducer phosphatase 1

1

4

Small-scale

0.724

High

507546

CDN1A
Cyclin-dependent kinase inhibitor 1

1

9

Small-scale

0.692

High

507555

DAPK1
Death-associated protein kinase 1

1

19

High-throughput

0.692

High

507583

EDC3
Enhancer of mRNA-decapping protein 3

4

0

High-throughput

0.670

High

507540

DDX6
Probable ATP-dependent RNA helicase DDX6

3

4

High-throughput

0.667

High

507576

DCP1B
mRNA-decapping enzyme 1B

3

2

High-throughput

0.667

High

507587

DCP1A
mRNA-decapping enzyme 1A

3

2

High-throughput

0.667

High

507561

MDM2
E3 ubiquitin-protein ligase Mdm2

2

4

Small-scale

0.656

High

507539

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

17

Small-scale

0.647

High

507554

BMX
Cytoplasmic tyrosine-protein kinase BMX

1

17

Small-scale

0.646

High

507579

DCAF4
DDB1- and CUL4-associated factor 4

3

0

High-throughput

0.638

High

507590

SNX6
Sorting nexin-6

2

5

Small-scale

0.631

High

345789

MYC
Myc proto-oncogene protein

2

9

Small-scale

0.624

High

437837

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.618

High

507549

CDN1B
Cyclin-dependent kinase inhibitor 1B

1

9

Small-scale

0.618

High

507564

CBX3
Chromobox protein homolog 3

1

3

Small-scale

0.586

High

507565

SKP2
S-phase kinase-associated protein 2

1

2

Small-scale

0.578

High

434457

FUMH
Fumarate hydratase, mitochondrial

1

2

High-throughput

0.573

High

507553

FXR2
RNA-binding protein FXR2

1

2

High-throughput

0.573

High

507584

HEXI2
Protein HEXIM2

1

2

High-throughput

0.573

High

507547

RS19
Small ribosomal subunit protein eS19

1

0

Small-scale

0.561

High

317893

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

5

Small-scale

0.561

High

507563

CDC20
Cell division cycle protein 20 homolog

1

8

Small-scale

0.561

High

507569

NUMA1
Nuclear mitotic apparatus protein 1

1

11

Small-scale

0.561

High

507586

FOXP3
Forkhead box protein P3

1

1

Small-scale

0.561

High

507589

FZR1
Fizzy-related protein homolog

1

7

Small-scale

0.561

High

437177

MDR1
ATP-dependent translocase ABCB1

1

0

Small-scale

0.554

High

507575

SND1
Staphylococcal nuclease domain-containing protein 1

1

2

Small-scale

0.552

High

471552

TFPT
TCF3 fusion partner

1

0

High-throughput

0.549

High

507578

BANP
Protein BANP

1

0

High-throughput

0.549

High

507591

ABCG2
Broad substrate specificity ATP-binding cassette transporter ABCG2

1

1

Small-scale

0.543

High

507544

GLYC
Serine hydroxymethyltransferase, cytosolic

1

1

High-throughput

0.541

High

396311

APOD
Apolipoprotein D

1

1

High-throughput

0.536

High

447648

ENOG
Gamma-enolase

1

3

High-throughput

0.536

High

507542

SPB3
Serpin B3

1

3

High-throughput

0.536

High

507550

UTRN
Utrophin

1

13

High-throughput

0.536

High

507594

S4A7
Sodium bicarbonate cotransporter 3

1

2

High-throughput

0.536

High

507566

TARB1
Probable methyltransferase TARBP1

1

0

High-throughput

0.513

High

507573

FBX50
F-box only protein 50

1

0

High-throughput

0.513

High

507582

PAUF
Pancreatic adenocarcinoma up-regulated factor

1

0

High-throughput

0.513

High

394011

A4
Amyloid-beta precursor protein

1

8

High-throughput

0.501

High

507557

UBC9
SUMO-conjugating enzyme UBC9

1

3

Small-scale

0.501

High

507558

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

14

Small-scale

0.501

High

507560

H33
Histone H3.3

1

3

Small-scale

0.501

High

507574

H32
Histone H3.2

1

3

Small-scale

0.501

High

507580

BAD
Bcl2-associated agonist of cell death

1

4

Small-scale

0.501

High

507581

AKTS1
Proline-rich AKT1 substrate 1

1

5

Small-scale

0.501

High

507588

SENP1
Sentrin-specific protease 1

1

1

Small-scale

0.501

High

507593

FBX7
F-box only protein 7

1

4

High-throughput

0.501

High

245780

CATL2
Cathepsin L2

1

1

High-throughput

0.489

High

507562

HEN1
Helix-loop-helix protein 1

1

3

High-throughput

0.481

High

206793

FOXO3
Forkhead box protein O3

1

8

Small-scale

0.479

High

277905

PIAS1
E3 SUMO-protein ligase PIAS1

1

4

Small-scale

0.479

High

507353

ERG
Transcriptional regulator ERG

1

2

Small-scale

0.479

High

507545

HSP74
Heat shock 70 kDa protein 4

1

12

Small-scale

0.479

High

507552

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

1

Small-scale

0.479

High

507556

MAX
Protein max

1

7

Small-scale

0.479

High

507559

CBX1
Chromobox protein homolog 1

1

3

Small-scale

0.479

High

507567

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

507568

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

3

Small-scale

0.479

High

507570

2A5B
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform

1

3

Small-scale

0.479

High

507585

UBP28
Ubiquitin carboxyl-terminal hydrolase 28

1

12

Small-scale

0.479

High

507595

PIAS3
E3 SUMO-protein ligase PIAS3

1

4

Small-scale

0.479

High

507571

Q5T203
Nescient helix loop helix 1

1

3

High-throughput

0.470

High

507548

STAT3
Signal transducer and activator of transcription 3

1

2

Small-scale

0.445

High

72273

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

1

1

High-throughput

0.437

High

66372

A2ML1
Alpha-2-macroglobulin-like protein 1

1

1

High-throughput

0.407

High

484803

AMY1B
Alpha-amylase 1B

1

1

High-throughput

0.407

High

507577

BEND7
BEN domain-containing protein 7

1

0

High-throughput

0.299

High

507551

PTSS1
Phosphatidylserine synthase 1

1

0

High-throughput

0.279

Low

507572

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024