Interactor 1: SHAN3 (Q9BYB0)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2)
Gene: SHANK3
Interactor 2: PICK1 (Q9NRD5)
PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein)
Gene: PICK1
Species: Homo sapiens
Source: mint
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.56 | 1.00 | 0.752 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21653829 |
| Identification Methods | two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid pooling approach |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PDZ~PDZ_6, PDZ~SAM_1, PDZ~SH3_2 |
| Common GO terms | GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0043005 - neuron projection |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Dm |  |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
