Protein: CUX1
Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (CDP/Cux p200) (Homeobox protein cux-1) [Cleaved into: CDP/Cux p110]

Gene: CUX1
Organism: Homo sapiens
Interactions: 185
UniProt ID: P39880

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

764626

SATB1
DNA-binding protein SATB1

1

7

Small-scale

0.724

High

764605

SOX2
Transcription factor SOX-2

5

20

Small-scale

0.709

High

147201

CUX2
Homeobox protein cut-like 2

1

20

High-throughput

0.691

High

212749

STX6
Syntaxin-6

4

4

High-throughput

0.686

High

764602

MAGAA
Melanoma-associated antigen 10

3

8

High-throughput

0.656

High

764620

H31
Histone H3.1

3

9

High-throughput

0.640

High

171006

TBXT
T-box transcription factor T

1

8

High-throughput

0.618

High

211803

TLX3
T-cell leukemia homeobox protein 3

1

20

High-throughput

0.618

High

213302

TLX2
T-cell leukemia homeobox protein 2

1

20

High-throughput

0.618

High

515563

SRF
Serum response factor

1

4

High-throughput

0.618

High

641333

PAX6
Paired box protein Pax-6

1

19

High-throughput

0.618

High

679066

TLX1
T-cell leukemia homeobox protein 1

1

20

High-throughput

0.618

High

764609

LHX2
LIM/homeobox protein Lhx2

1

17

High-throughput

0.618

High

764631

HME1
Homeobox protein engrailed-1

1

10

High-throughput

0.618

High

764711

LHX3
LIM/homeobox protein Lhx3

1

18

High-throughput

0.618

High

506904

LAMP1
Lysosome-associated membrane glycoprotein 1

2

7

High-throughput

0.611

High

764670

EXT2
Exostosin-2

2

2

High-throughput

0.611

High

354819

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

3

3

High-throughput

0.599

High

764654

S39A4
Zinc transporter ZIP4

3

9

High-throughput

0.599

High

764683

WDR83
WD repeat domain-containing protein 83

3

13

High-throughput

0.599

High

764676

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

11

Small-scale

0.586

High

414199

RB
Retinoblastoma-associated protein

1

3

Small-scale

0.586

High

764617

H4
Histone H4

2

10

High-throughput

0.584

High

764646

HDAC1
Histone deacetylase 1

2

20

High-throughput

0.584

High

764630

TLE4
Transducin-like enhancer protein 4

1

20

Small-scale

0.561

High

764668

CBP
CREB-binding protein

1

20

Small-scale

0.561

High

169392

BET1
BET1 homolog

2

5

High-throughput

0.558

High

764650

RAB30
Ras-related protein Rab-30

2

11

High-throughput

0.558

High

764652

S39AC
Zinc transporter ZIP12

2

9

High-throughput

0.558

High

131216

BIN1
Myc box-dependent-interacting protein 1

1

2

High-throughput

0.541

High

295504

RECQ5
ATP-dependent DNA helicase Q5

1

10

High-throughput

0.541

High

764615

MAX
Protein max

1

11

High-throughput

0.541

High

538490

CCNB1
G2/mitotic-specific cyclin-B1

1

2

Small-scale

0.536

High

126437

FOXE1
Forkhead box protein E1

1

20

High-throughput

0.536

High

175960

FOXN1
Forkhead box protein N1

1

19

High-throughput

0.536

High

317921

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

9

High-throughput

0.536

High

326037

TSN15
Tetraspanin-15

1

9

High-throughput

0.536

High

536484

IRF2
Interferon regulatory factor 2

1

3

High-throughput

0.536

High

740109

NUP62
Nuclear pore glycoprotein p62

1

5

High-throughput

0.536

High

764613

FOXG1
Forkhead box protein G1

1

20

High-throughput

0.536

High

764625

FOXK2
Forkhead box protein K2

1

20

High-throughput

0.536

High

764632

SUH
Recombining binding protein suppressor of hairless

1

1

High-throughput

0.536

High

764633

FMR1
Fragile X messenger ribonucleoprotein 1

1

6

High-throughput

0.536

High

764638

FOXO1
Forkhead box protein O1

1

20

High-throughput

0.536

High

764675

Z512B
Zinc finger protein 512B

1

14

High-throughput

0.536

High

764685

SSBP3
Single-stranded DNA-binding protein 3

1

14

High-throughput

0.536

High

764688

FOXQ1
Forkhead box protein Q1

1

20

High-throughput

0.536

High

764691

ILKAP
Integrin-linked kinase-associated serine/threonine phosphatase 2C

1

2

High-throughput

0.536

High

764696

FOXP1
Forkhead box protein P1

1

20

High-throughput

0.536

High

764701

TF7L2
Transcription factor 7-like 2

1

20

High-throughput

0.536

High

764710

FOXJ2
Forkhead box protein J2

1

20

High-throughput

0.536

High

764713

FOXD3
Forkhead box protein D3

1

20

High-throughput

0.536

High

764723

TACC3
Transforming acidic coiled-coil-containing protein 3

1

16

High-throughput

0.536

High

764681

RNZ2
Zinc phosphodiesterase ELAC protein 2

1

0

High-throughput

0.518

High

409021

K2C8
Keratin, type II cytoskeletal 8

1

6

High-throughput

0.515

High

764706

SPS2L
SPATS2-like protein

1

0

High-throughput

0.513

High

414798

CDK1
Cyclin-dependent kinase 1

1

13

Small-scale

0.501

High

764610

CDK7
Cyclin-dependent kinase 7

1

17

Small-scale

0.501

High

764616

SUMO2
Small ubiquitin-related modifier 2

1

2

High-throughput

0.501

High

764622

CCNA1
Cyclin-A1

1

2

Small-scale

0.501

High

764669

KAT2B
Histone acetyltransferase KAT2B

1

16

Small-scale

0.501

High

163765

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

5

High-throughput

0.489

High

306512

NDUB8
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial

1

1

High-throughput

0.489

High

645894

IL3RA
Interleukin-3 receptor subunit alpha

1

1

High-throughput

0.489

High

764603

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

2

High-throughput

0.489

High

764614

CXCR4
C-X-C chemokine receptor type 4

1

5

High-throughput

0.489

High

764649

P2RY6
P2Y purinoceptor 6

1

10

High-throughput

0.489

High

764651

C3AR
C3a anaphylatoxin chemotactic receptor

1

4

High-throughput

0.489

High

764662

SYCE1
Synaptonemal complex central element protein 1

1

2

High-throughput

0.489

High

764671

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

5

High-throughput

0.489

High

764682

KXDL1
KxDL motif-containing protein 1

1

1

High-throughput

0.489

High

764697

CSTN2
Calsyntenin-2

1

2

High-throughput

0.489

High

764642

CAF1B
Chromatin assembly factor 1 subunit B

1

11

High-throughput

0.481

High

122535

MEN1
Menin

1

4

High-throughput

0.479

High

134365

ACKR2
Atypical chemokine receptor 2

1

7

High-throughput

0.479

High

148479

CTRO
Citron Rho-interacting kinase

1

15

High-throughput

0.479

High

204118

KLF4
Krueppel-like factor 4

1

14

High-throughput

0.479

High

206465

B4GA1
Beta-1,4-glucuronyltransferase 1

1

1

High-throughput

0.479

High

225711

SOX15
Transcription factor SOX-15

1

20

High-throughput

0.479

High

232027

KDM1A
Lysine-specific histone demethylase 1A

1

7

High-throughput

0.479

High

305377

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.479

High

348548

RASN
GTPase NRas

1

20

High-throughput

0.479

High

377155

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

443143

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

455168

PARP1
Poly [ADP-ribose] polymerase 1

1

6

High-throughput

0.479

High

486755

MYB
Transcriptional activator Myb

1

5

High-throughput

0.479

High

487193

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

545942

MYOD1
Myoblast determination protein 1

1

3

High-throughput

0.479

High

569316

CEBPB
CCAAT/enhancer-binding protein beta

1

8

High-throughput

0.479

High

590675

BTF3
Transcription factor BTF3

1

7

High-throughput

0.479

High

620309

GATA2
Endothelial transcription factor GATA-2

1

11

High-throughput

0.479

High

652773

APEX1
DNA repair nuclease/redox regulator APEX1

1

2

High-throughput

0.479

High

658466

TEAD1
Transcriptional enhancer factor TEF-1

1

4

High-throughput

0.479

High

707541

H2B1B
Histone H2B type 1-B

1

20

High-throughput

0.479

High

716839

CTNB1
Catenin beta-1

1

8

High-throughput

0.479

High

727483

HNF1B
Hepatocyte nuclear factor 1-beta

1

19

High-throughput

0.479

High

727707

SOX5
Transcription factor SOX-5

1

20

High-throughput

0.479

High

727835

SOX6
Transcription factor SOX-6

1

20

High-throughput

0.479

High

764601

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

High-throughput

0.479

High

764604

YAP1
Transcriptional coactivator YAP1

1

17

High-throughput

0.479

High

764606

SOX9
Transcription factor SOX-9

1

20

High-throughput

0.479

High

764607

CENPA
Histone H3-like centromeric protein A

1

9

High-throughput

0.479

High

764608

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

High-throughput

0.479

High

764612

PAR2
Proteinase-activated receptor 2

1

8

High-throughput

0.479

High

764618

H2B1C
Histone H2B type 1-C/E/F/G/I

1

20

High-throughput

0.479

High

764619

RAB1A
Ras-related protein Rab-1A

1

7

High-throughput

0.479

High

764623

H33
Histone H3.3

1

9

High-throughput

0.479

High

764624

TFAM
Transcription factor A, mitochondrial

1

20

High-throughput

0.479

High

764627

CAV1
Caveolin-1

1

2

High-throughput

0.479

High

764629

TLE3
Transducin-like enhancer protein 3

1

20

High-throughput

0.479

High

764634

SOX4
Transcription factor SOX-4

1

20

High-throughput

0.479

High

764636

RBBP4
Histone-binding protein RBBP4

1

6

High-throughput

0.479

High

764637

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

1

High-throughput

0.479

High

764639

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

17

High-throughput

0.479

High

764640

TP53B
TP53-binding protein 1

1

8

High-throughput

0.479

High

764641

FOXL1
Forkhead box protein L1

1

19

High-throughput

0.479

High

764643

RFA4
Replication protein A 30 kDa subunit

1

7

High-throughput

0.479

High

764644

CBX3
Chromobox protein homolog 3

1

1

High-throughput

0.479

High

764645

SKP2
S-phase kinase-associated protein 2

1

5

Small-scale

0.479

High

764647

CUL1
Cullin-1

1

12

Small-scale

0.479

High

764648

NFIX
Nuclear factor 1 X-type

1

18

High-throughput

0.479

High

764656

RICTR
Rapamycin-insensitive companion of mTOR

1

4

High-throughput

0.479

High

764658

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.479

High

764660

SMC5
Structural maintenance of chromosomes protein 5

1

13

High-throughput

0.479

High

764664

SP7
Transcription factor Sp7

1

10

High-throughput

0.479

High

764665

RBCC1
RB1-inducible coiled-coil protein 1

1

17

High-throughput

0.479

High

764666

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

4

High-throughput

0.479

High

764667

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

764672

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

15

High-throughput

0.479

High

764674

ZDH12
Palmitoyltransferase ZDHHC12

1

4

High-throughput

0.479

High

764678

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

764679

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

1

High-throughput

0.479

High

764680

FEV
Protein FEV

1

9

High-throughput

0.479

High

764686

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

12

High-throughput

0.479

High

764690

WWTR1
WW domain-containing transcription regulator protein 1

1

16

High-throughput

0.479

High

764692

RAB1B
Ras-related protein Rab-1B

1

7

High-throughput

0.479

High

764694

GAN
Gigaxonin

1

6

High-throughput

0.479

High

764699

ECT2
Protein ECT2

1

12

High-throughput

0.479

High

764702

ITM2C
Integral membrane protein 2C

1

4

High-throughput

0.479

High

764703

SAR1A
Small COPII coat GTPase SAR1A

1

16

High-throughput

0.479

High

764704

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

2

High-throughput

0.479

High

764707

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.479

High

764708

GPC5B
G-protein coupled receptor family C group 5 member B

1

4

High-throughput

0.479

High

764712

ZRAN1
Ubiquitin thioesterase ZRANB1

1

11

High-throughput

0.479

High

764714

ANC2
Anaphase-promoting complex subunit 2

1

13

High-throughput

0.479

High

764716

RCOR1
REST corepressor 1

1

20

High-throughput

0.479

High

764717

NUP50
Nuclear pore complex protein Nup50

1

1

High-throughput

0.479

High

764722

ZN330
Zinc finger protein 330

1

2

High-throughput

0.479

High

764628

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

1

0

High-throughput

0.458

High

764655

FBX38
F-box only protein 38

1

0

High-throughput

0.458

High

764720

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

401556

JUN
Transcription factor Jun

1

11

High-throughput

0.445

High

717510

BMI1
Polycomb complex protein BMI-1

1

17

High-throughput

0.445

High

764611

NCBP2
Nuclear cap-binding protein subunit 2

1

2

High-throughput

0.445

High

764689

ZDHC5
Palmitoyltransferase ZDHHC5

1

6

High-throughput

0.445

High

764705

RN146
E3 ubiquitin-protein ligase RNF146

1

1

Small-scale

0.445

High

764709

GRHL1
Grainyhead-like protein 1 homolog

1

5

High-throughput

0.445

High

132427

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.437

High

171950

GP182
G-protein coupled receptor 182

1

8

High-throughput

0.437

High

362131

ACHA
Acetylcholine receptor subunit alpha

1

2

High-throughput

0.437

High

384409

NTRK1
High affinity nerve growth factor receptor

1

16

High-throughput

0.437

High

540279

GPIX
Platelet glycoprotein IX

1

8

High-throughput

0.437

High

764621

GBRE
Gamma-aminobutyric acid receptor subunit epsilon

1

2

High-throughput

0.437

High

764635

TNR9
Tumor necrosis factor receptor superfamily member 9

1

6

High-throughput

0.437

High

764657

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

764659

P2RY8
P2Y purinoceptor 8

1

7

High-throughput

0.437

High

764661

S15A3
Solute carrier family 15 member 3

1

2

High-throughput

0.437

High

764673

PLPR2
Phospholipid phosphatase-related protein type 2

1

1

High-throughput

0.437

High

764677

DIESL
DGAT1/2-independent enzyme synthesizing storage lipids

1

1

High-throughput

0.437

High

764698

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.437

High

764700

LPAR2
Lysophosphatidic acid receptor 2

1

1

High-throughput

0.437

High

764715

KCND3
Potassium voltage-gated channel subfamily D member 3

1

2

Small-scale

0.437

High

764718

CLC4A
C-type lectin domain family 4 member A

1

5

High-throughput

0.437

High

207578

CAH12
Carbonic anhydrase 12

1

2

High-throughput

0.417

High

48862

POTB3
POTE ankyrin domain family member B3

1

5

High-throughput

0.407

High

99565

F5H1C8
Solute carrier family 15 member 3

1

2

High-throughput

0.407

High

283643

JTB
Protein JTB

1

0

High-throughput

0.279

Low

764653

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.279

Low

764663

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.279

Low

764687

TMM59
Transmembrane protein 59

1

0

High-throughput

0.279

Low

764693

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

764695

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.279

Low

764719

TNF18
Tumor necrosis factor ligand superfamily member 18

1

0

High-throughput

0.279

Low

764721

COA3
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial

1

0

High-throughput

0.279

Low

764684

LRC61
Leucine-rich repeat-containing protein 61

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024