HitPredict

Interactor 1: SHAN3 (Q9BYB0)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2)
Gene: SHANK3

Interactor 2: TR150 (Q9Y2W1)
Thyroid hormone receptor-associated protein 3 (BCLAF1 and THRAP3 family member 2) (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150)
Gene: THRAP3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.50	0.494

Property	Details
Experiments	21653829
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1731 Hs			1 955
+	Hs
		883682 RIPK4_HUMAN (25-420): 3.28e-78: 280: 16.00		TR150_HUMAN (1-955): 9.81e-127: 408: 100.00
+	Mm
		936894 SHAN3_MOUSE (1-1731): 8.04e-176: 579: 93.71		NACAM_MOUSE (6-853): 3.81e-19: 95.8: 8.59
+	Mm
		1116160 SHAN3_MOUSE (1-1731): 8.04e-176: 579: 93.71		PCLO_MOUSE (105-876): 3.39e-12: 73.1: 9.68
+	Hs
		883657 RIPK4_HUMAN (25-420): 3.28e-78: 280: 16.00		BCLF1_HUMAN (38-949): 3.55e-78: 276: 33.19
+	Hs
		1377439 ASB3_HUMAN (256-388): 1.28e-17: 90.3: 16.67		TR150_HUMAN (1-955): 9.81e-127: 408: 100.00
+	Hs
		166913 ANR28_HUMAN (27-335): 3.42e-77: 281: 16.48		ANK2_HUMAN (47-877): 6.14e-50: 195: 12.46
+	Hs
		883487 RIPK4_HUMAN (25-420): 3.28e-78: 280: 16.00		ANK2_HUMAN (47-877): 6.14e-50: 195: 12.46
+	Hs
		862028 DAPK1_HUMAN (103-579): 1.12e-67: 254: 14.94		ANK2_HUMAN (47-877): 6.14e-50: 195: 12.46
+	Hs
		1191747 ANR50_HUMAN (228-1055): 8.36e-32: 138: 9.83		RBBP6_HUMAN (20-841): 1.66e-72: 264: 13.81
+	Hs
		1115387 AKD1A_HUMAN (5-402): 1.62e-88: 301: 18.03		TITIN_HUMAN (105-799): 3.29e-11: 70: 7.20
+	Hs
		1348485 ASB3_HUMAN (256-388): 1.28e-17: 90.3: 16.67		BCLF1_HUMAN (38-949): 3.55e-78: 276: 33.19
+	Hs
		166985 ANR28_HUMAN (27-335): 3.42e-77: 281: 16.48		TITIN_HUMAN (105-799): 3.29e-11: 70: 7.20
+	Hs
		1330865 Q9H4D1_HUMAN (275-465): 9.3e-09: 62.6: 15.39		BCLF1_HUMAN (38-949): 3.55e-78: 276: 33.19
+	Hs
		965154 Q9H4D1_HUMAN (275-465): 9.3e-09: 62.6: 15.39		ANK2_HUMAN (47-877): 6.14e-50: 195: 12.46
+	Hs
		1021422 ANK3_HUMAN (120-561): 2.39e-41: 170: 15.54		MICA3_HUMAN (169-857): 2.66e-09: 63.4: 7.24
+	Dm
		65570 A8JNM5_DROME (649-1691): 7.65e-24: 112: 11.17		FUTSC_DROME (2-877): 4.63e-26: 118: 10.92
+	Hs
		556716 ANK1_HUMAN (175-527): 4.16e-38: 159: 17.28		TITIN_HUMAN (105-799): 3.29e-11: 70: 7.20
+	Hs
		1056981 TNKS2_HUMAN (220-558): 1.49e-36: 153: 12.29		MDC1_HUMAN (2-649): 1.14e-11: 71.2: 8.49
+	Hs
		310053 TNKS1_HUMAN (220-563): 2.59e-36: 153: 12.67		MDC1_HUMAN (2-649): 1.14e-11: 71.2: 8.49
+	Dm
		113976 M9PB30_DROME (349-1110): 2.53e-09: 65.1: 11.73		M9PB30_DROME (109-621): 2.93e-12: 73.5: 7.57