HitPredict

Interactor 1: HELZ2 (Q9BYK8)
3'-5' exoribonuclease HELZ2 (EC 3.1.13.1) (ATP-dependent RNA helicase PRIC285) (EC 3.6.4.13) (Helicase with zinc finger 2, transcriptional coactivator) (Helicase with zinc finger domain 2) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein)
Gene: HELZ2

Interactor 2: SIR7 (Q9NRC8)
NAD-dependent protein deacetylase sirtuin-7 (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-7) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 7) (SIR2-like protein 7)
Gene: SIRT7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22586326
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0046872 - metal ion binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 2896 Hs			1 400
+	Hs
		1344544 RRP44_HUMAN (1191-2064): 0: 682: 17.83		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		1272371 RENT1_HUMAN (2148-2891): 0: 606: 24.35		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		1335979 MOV10_HUMAN (2257-2886): 7.48e-121: 411: 21.93		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		1236420 RENT1_HUMAN (2148-2891): 0: 606: 24.35		SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87
+	Hs
		1236511 MOV10_HUMAN (2257-2886): 7.48e-121: 411: 21.93		SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87