Protein: MAL
Myelin and lymphocyte protein (T-lymphocyte maturation-associated protein)

Gene: MAL
Organism: Homo sapiens
Interactions: 90
UniProt ID: P21145

Gene Ontology (top 5):
GO:0001766 - membrane raft polarization
GO:0002175 - protein localization to paranode region of axon
GO:0005783 - endoplasmic reticulum
GO:0006915 - apoptotic process
GO:0007417 - central nervous system development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

636225

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

4

1

High-throughput

0.698

High

636245

EDA
Ectodysplasin-A

4

0

High-throughput

0.668

High

636238

FBCD1
Fibrinogen C domain-containing protein 1

3

0

High-throughput

0.646

High

636260

SMIM3
Small integral membrane protein 3

3

0

High-throughput

0.646

High

636199

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

3

8

High-throughput

0.616

High

211911

SPIT1
Kunitz-type protease inhibitor 1

2

1

High-throughput

0.606

High

220147

TNF14
Tumor necrosis factor ligand superfamily member 14

2

1

High-throughput

0.606

High

338719

CLD14
Claudin-14

2

6

High-throughput

0.606

High

636204

OPRM
Mu-type opioid receptor

2

3

High-throughput

0.606

High

636207

EMP1
Epithelial membrane protein 1

2

1

High-throughput

0.606

High

636209

CXAR
Coxsackievirus and adenovirus receptor

2

1

High-throughput

0.606

High

636213

KCNA1
Potassium voltage-gated channel subfamily A member 1

2

1

High-throughput

0.606

High

636215

I10R1
Interleukin-10 receptor subunit alpha

2

1

High-throughput

0.606

High

636217

KCA10
Potassium voltage-gated channel subfamily A member 10

2

1

High-throughput

0.606

High

636224

F209A
Protein FAM209A

2

1

High-throughput

0.606

High

636237

LRC25
Leucine-rich repeat-containing protein 25

2

1

High-throughput

0.606

High

636241

FNDC9
Fibronectin type III domain-containing protein 9

2

2

High-throughput

0.606

High

636244

TM174
Transmembrane protein 174

2

1

High-throughput

0.606

High

636247

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

5

High-throughput

0.606

High

636252

M4A4A
Membrane-spanning 4-domains subfamily A member 4A

2

2

High-throughput

0.606

High

636253

FCRL2
Fc receptor-like protein 2

2

1

High-throughput

0.606

High

636255

PRRT1
Proline-rich transmembrane protein 1

2

1

High-throughput

0.606

High

636258

B2L13
Bcl-2-like protein 13

2

1

High-throughput

0.606

High

636267

TM248
Transmembrane protein 248

2

1

High-throughput

0.606

High

636254

MYD88
Myeloid differentiation primary response protein MyD88

2

1

Small-scale

0.586

High

636223

TM52B
Transmembrane protein 52B

2

0

High-throughput

0.580

High

636226

TSPO2
Translocator protein 2

2

0

High-throughput

0.580

High

636227

CNDH2
Condensin-2 complex subunit H2

2

0

High-throughput

0.580

High

636228

TM207
Transmembrane protein 207

2

0

High-throughput

0.580

High

636229

CLM9
CMRF35-like molecule 9

2

0

High-throughput

0.580

High

636239

TEX29
Testis-expressed protein 29

2

0

High-throughput

0.580

High

636248

T4S18
Transmembrane 4 L6 family member 18

2

0

High-throughput

0.580

High

636250

SHSA4
Protein shisa-4

2

0

High-throughput

0.580

High

636261

LMA2L
VIP36-like protein

2

0

High-throughput

0.580

High

636263

LRTM1
Leucine-rich repeat and transmembrane domain-containing protein 1

2

0

High-throughput

0.580

High

636266

CC50A
Cell cycle control protein 50A

2

0

High-throughput

0.580

High

192059

PA2GX
Group 10 secretory phospholipase A2

2

1

High-throughput

0.553

High

337861

CLD7
Claudin-7

2

6

High-throughput

0.553

High

338248

CLD9
Claudin-9

2

6

High-throughput

0.553

High

464674

CXB1
Gap junction beta-1 protein

2

3

High-throughput

0.553

High

636197

EVI2A
Protein EVI2A

2

1

High-throughput

0.553

High

636206

CXA8
Gap junction alpha-8 protein

2

3

High-throughput

0.553

High

636208

CLD20
Claudin-20

2

6

High-throughput

0.553

High

636212

CD69
Early activation antigen CD69

2

7

High-throughput

0.553

High

636214

AQP6
Aquaporin-6

2

4

High-throughput

0.553

High

636216

NTCP
Hepatic sodium/bile acid cotransporter

2

3

High-throughput

0.553

High

636219

STX1A
Syntaxin-1A

2

2

High-throughput

0.553

High

636222

TIGIT
T-cell immunoreceptor with Ig and ITIM domains

2

1

High-throughput

0.553

High

636230

I20RB
Interleukin-20 receptor subunit beta

2

1

High-throughput

0.553

High

636232

BT2A1
Butyrophilin subfamily 2 member A1

2

1

High-throughput

0.553

High

636233

CPLX4
Complexin-4

2

1

High-throughput

0.553

High

636242

GP152
Probable G-protein coupled receptor 152

2

5

High-throughput

0.553

High

636243

CLC4C
C-type lectin domain family 4 member C

2

2

High-throughput

0.553

High

636262

SYNG1
Synapse differentiation-inducing gene protein 1

2

1

High-throughput

0.553

High

636264

S35C2
Solute carrier family 35 member C2

2

3

High-throughput

0.553

High

636268

DGLA
Diacylglycerol lipase-alpha

2

2

High-throughput

0.553

High

636240

LSME1
Leucine-rich single-pass membrane protein 1

1

0

High-throughput

0.549

High

636203

MC4R
Melanocortin receptor 4

1

4

High-throughput

0.541

High

636211

BTK
Tyrosine-protein kinase BTK

1

4

Small-scale

0.515

High

60215

TM213
Transmembrane protein 213

1

0

High-throughput

0.460

High

636196

MAL
Myelin and lymphocyte protein

1

0

Small-scale

0.458

High

636200

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

0

Small-scale

0.458

High

463327

LYN
Tyrosine-protein kinase Lyn

1

4

Small-scale

0.445

High

557086

SRC
Proto-oncogene tyrosine-protein kinase Src

1

4

Small-scale

0.445

High

385453

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

2

High-throughput

0.439

High

636205

KSYK
Tyrosine-protein kinase SYK

1

7

Small-scale

0.407

High

636210

FAK1
Focal adhesion kinase 1

1

6

Small-scale

0.407

High

49516

SHSA3
Protein shisa-3 homolog

2

0

High-throughput

0.316

High

260713

RAMP1
Receptor activity-modifying protein 1

2

0

High-throughput

0.316

High

485964

CD3G
T-cell surface glycoprotein CD3 gamma chain

2

0

High-throughput

0.316

High

622025

CD53
Leukocyte surface antigen CD53

2

0

High-throughput

0.316

High

636198

TNR5
Tumor necrosis factor receptor superfamily member 5

2

0

High-throughput

0.316

High

636201

SDC4
Syndecan-4

2

0

High-throughput

0.316

High

636202

3HIDH
3-hydroxyisobutyrate dehydrogenase, mitochondrial

2

0

High-throughput

0.316

High

636218

SGCB
Beta-sarcoglycan

2

0

High-throughput

0.316

High

636220

AMHR2
Anti-Muellerian hormone type-2 receptor

2

0

High-throughput

0.316

High

636231

GSG1L
Germ cell-specific gene 1-like protein

2

0

High-throughput

0.316

High

636234

KCMB4
Calcium-activated potassium channel subunit beta-4

2

0

High-throughput

0.316

High

636235

JAML
Junctional adhesion molecule-like

2

0

High-throughput

0.316

High

636236

NKAI4
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4

2

0

High-throughput

0.316

High

636249

ASTRA
Protein Aster-A

2

0

High-throughput

0.316

High

636251

PERP
p53 apoptosis effector related to PMP-22

2

0

High-throughput

0.316

High

636256

CSTN3
Calsyntenin-3

2

0

High-throughput

0.316

High

636257

T106C
Transmembrane protein 106C

2

0

High-throughput

0.316

High

636259

CABP8
Calcium-binding protein 8

2

0

High-throughput

0.316

High

636265

NPDC1
Neural proliferation differentiation and control protein 1

2

0

High-throughput

0.316

High

636221

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

0

High-throughput

0.299

High

636246

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

High-throughput

0.288

High

126292

TLR4
Toll-like receptor 4

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025