HitPredict

Interactor 1: WWP2 (O00308)
NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (Atrophin-1-interacting protein 2) (AIP2) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2)
Gene: WWP2

Interactor 2: HNRPL (P14866)
Heterogeneous nuclear ribonucleoprotein L (hnRNP L)
Gene: HNRNPL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31048545, 35258167
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016020 - membrane GO:0045892 - negative regulation of DNA-templated transcription GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 870 Hs			1 589
+	Hs
		576504 ITCH_HUMAN (1-870): 0: 899: 53.91		HNRPL_HUMAN (1-589): 6.82e-112: 348: 100.00
+	Hs
		131798 WWP2_HUMAN (1-870): 0: 984: 100.00		MATR3_HUMAN (71-364): 1.68e-59: 214: 20.64
+	Hs
		131699 WWP2_HUMAN (1-870): 0: 984: 100.00		PABP1_HUMAN (53-384): 4.56e-42: 162: 16.19
+	Hs
		132010 WWP2_HUMAN (1-870): 0: 984: 100.00		PABP4_HUMAN (53-389): 1.51e-41: 161: 13.71
+	Hs
		846470 WWP1_HUMAN (1-870): 0: 883: 58.27		MATR3_HUMAN (71-364): 1.68e-59: 214: 20.64
+	Hs
		576313 NEDD4_HUMAN (90-867): 0: 728: 36.26		HNRPL_HUMAN (1-589): 6.82e-112: 348: 100.00
+	Hs
		550415 ITCH_HUMAN (1-870): 0: 899: 53.91		PABP1_HUMAN (53-384): 4.56e-42: 162: 16.19
+	Hs
		131744 WWP2_HUMAN (1-870): 0: 984: 100.00		PTBP1_HUMAN (59-445): 1.78e-10: 65.8: 12.35