HitPredict

Interactor 1: BACH2 (Q9BYV9)
Transcription regulator protein BACH2 (BTB and CNC homolog 2)
Gene: BACH2

Interactor 2: MAFF (Q9ULX9)
Transcription factor MafF (U-Maf) (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F)
Gene: MAFF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.899

The method score is based on:

Property Details
Experiments 23661758, 26186194, 28514442, 33961781
Identification Methods fluorescent resonance energy transfer, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains bZIP_Maf~bZIP_Maf
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 841
Hs

1 164
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024