HitPredict

Interactor 1: FNDC5 (Q8NAU1)
Fibronectin type III domain-containing protein 5 (Fibronectin type III repeat-containing protein 2) [Cleaved into: Irisin]
Gene: FNDC5

Interactor 2: DMBT1 (Q9UGM3)
Scavenger receptor cysteine-rich domain-containing protein DMBT1 (Deleted in malignant brain tumors 1 protein) (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein)
Gene: DMBT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 260 Hs			1 2413
+	Mm
		945737 FNDC5_MOUSE (1-260): 3.72e-159: 443: 89.23		LOXL2_MOUSE (14-463): 2.36e-89: 312: 25.86
+	Mm
		1317570 FNDC5_MOUSE (1-260): 3.72e-159: 443: 89.23		LOXL4_MOUSE (14-467): 2e-81: 288: 27.45
+	Mm
		1021178 FNDC5_MOUSE (1-260): 3.72e-159: 443: 89.23		NRP1_MOUSE (1761-2028): 3.41e-31: 136: 17.23
+	Mm
		1060061 FNDC5_MOUSE (1-260): 3.72e-159: 443: 89.23		LG3BP_MOUSE (1887-2043): 5.54e-23: 108: 40.13
+	Mm
		1317927 FNDC5_MOUSE (1-260): 3.72e-159: 443: 89.23		LOXL3_MOUSE (1848-1991): 3.32e-11: 71: 34.72