HitPredict

Interactor 1: ADA33 (Q9BZ11)
Disintegrin and metalloproteinase domain-containing protein 33 (ADAM 33) (EC 3.4.24.-)
Gene: ADAM33

Interactor 2: FBX2 (Q9UK22)
F-box only protein 2
Gene: FBXO2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006508 - proteolysis
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 813 Hs			1 296
+	Hs
		1034742 ADAM9_HUMAN (1-786): 0: 559: 31.66		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1034775 ADA15_HUMAN (20-810): 3.19e-153: 471: 37.28		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81
+	Hs
		253931 ADA23_HUMAN (37-740): 1.59e-137: 429: 28.57		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1356238 ATS7_HUMAN (31-808): 1.11e-111: 376: 16.95		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1344602 ATS7_HUMAN (31-808): 1.11e-111: 376: 16.95		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81
+	Hs
		944528 ADA17_HUMAN (298-583): 2.88e-24: 111: 30.19		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		152350 ADA10_HUMAN (196-519): 4.29e-23: 107: 27.63		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		944525 ADA17_HUMAN (298-583): 2.88e-24: 111: 30.19		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81
+	Hs
		152340 ADA10_HUMAN (196-519): 4.29e-23: 107: 27.63		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81