HitPredict

Interactor 1: TB182 (Q9C0C2)
182 kDa tankyrase-1-binding protein
Gene: TNKS1BP1

Interactor 2: TNKS2 (Q9H2K2)
Poly [ADP-ribose] polymerase tankyrase-2 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 6) (ARTD6) (Poly [ADP-ribose] polymerase 5B) (Protein poly-ADP-ribosyltransferase tankyrase-2) (EC 2.4.2.-) (TNKS-2) (TRF1-interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase II) (Tankyrase-2) (TANK2) (Tankyrase-like protein) (Tankyrase-related protein)
Gene: TNKS2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 0.60 0.647

The method score is based on:

Property Details
Experiments 11854288, 12080061, 22153077
Identification Methods two hybrid, pull down, fluorescence polarization spectroscopy
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0019899 - enzyme binding
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1729
Hs

1 1166
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024