HitPredict

Interactor 1: TB182 (Q9C0C2)
182 kDa tankyrase-1-binding protein
Gene: TNKS1BP1

Interactor 2: CNOT2 (Q9NZN8)
CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2)
Gene: CNOT2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	26496610, 29395067, 27173435, 33787085
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane and 1 others more... GO:0030014 - CCR4-NOT complex
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1729 Hs			1 540
+	Hs
		257404 TB182_HUMAN (1-1721): 0: 1143: 100.00		CNOT3_HUMAN (4-524): 3.46e-106: 336: 16.19
+	Hs
		257714 ANR17_HUMAN (1-411): 1.22e-09: 65.8: 12.56		CNOT2_HUMAN (1-540): 0: 528: 100.00
+	Mm
		1225088 MAP1A_MOUSE (7-764): 8.51e-12: 73.1: 11.57		CNOT3_MOUSE (4-524): 3.42e-109: 344: 17.14
+	Mm
		101458 F8VPR5_MOUSE (353-750): 7.16e-10: 66.5: 13.05		CNOT3_MOUSE (4-524): 3.42e-109: 344: 17.14
+	Hs
		257299 ANR17_HUMAN (1-411): 1.22e-09: 65.8: 12.56		CNOT3_HUMAN (4-524): 3.46e-106: 336: 16.19
+	Dm
		113976 M9PB30_DROME (519-852): 2.2e-09: 65.1: 9.32		M9PB30_DROME (37-438): 2.6e-11: 69: 13.35
+	Hs
		1336185 MAGE1_HUMAN (26-344): 2.44e-09: 64.5: 18.41		MAGE1_HUMAN (30-384): 2.34e-09: 62.1: 13.13