HitPredict

Interactor 1: FMR1 (Q9NFU0)
Fragile X messenger ribonucleoprotein 1 homolog (FMRP) (dFMR1)
Gene: FMR1

Interactor 2: DDX3 (Q9VHP0)
ATP-dependent RNA helicase bel (EC 3.6.4.13) (Protein belle)
Gene: bel

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	19026789, 25294943
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0010629 - negative regulation of gene expression GO:0016442 - RISC complex and 2 others more... GO:0043025 - neuronal cell body GO:0043186 - P granule
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 684 Dm			1 798
+	Dm
		72427 B3LF78_DROME (39-684): 0: 897: 100.00		DDX3_DROME (1-798): 0: 590: 100.00
+	Hs
		571412 FMR1_HUMAN (1-456): 0: 709: 40.27		DDX5_HUMAN (200-792): 4.78e-157: 472: 32.06
+	Hs
		844176 FXR2_HUMAN (4-484): 0: 664: 43.92		DDX17_HUMAN (231-793): 4.09e-158: 479: 32.87
+	Hs
		989173 FMR1_HUMAN (1-456): 0: 709: 40.27		DDX41_HUMAN (287-719): 2.11e-90: 298: 39.50
+	Hs
		133996 FMR1_HUMAN (1-456): 0: 709: 40.27		DDX3X_HUMAN (1-164): 2.25e-22: 104: 30.91
+	Hs
		133938 FXR1_HUMAN (1-412): 0: 691: 46.01		DDX3X_HUMAN (1-164): 2.25e-22: 104: 30.91
+	Mm
		729498 FMR1_MOUSE (1-456): 0: 672: 38.22		DDX3X_MOUSE (1-164): 3.58e-23: 106: 32.32
+	Hs
		133939 FXR2_HUMAN (4-484): 0: 664: 43.92		DDX3X_HUMAN (1-164): 2.25e-22: 104: 30.91
+	Mm
		1143617 Q8BPK8_MOUSE (1-342): 0: 614: 45.48		DDX3X_MOUSE (1-164): 3.58e-23: 106: 32.32