HitPredict

Interactor 1: MED6 (Q8MSX2)
Mediator of RNA polymerase II transcription subunit 6 (Mediator complex subunit 6) (dMED6)
Gene: MED6

Interactor 2: MED4 (Q9VS38)
Mediator of RNA polymerase II transcription subunit 4 (Mediator complex subunit 4) (dp34)
Gene: MED4

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.624

The method score is based on:

Property Details
Experiments 12021283, 22036573, 38944040
Identification Methods biochemical, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex
GO:0045893 - positive regulation of DNA-templated transcription
and 1 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 249
Dm

1 258
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025