HitPredict

Interactor 1: PRD14 (Q9GZV8)
PR domain zinc finger protein 14 (EC 2.1.1.-) (PR domain-containing protein 14)
Gene: PRDM14

Interactor 2: PRDM6 (Q9NQX0)
Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6)
Gene: PRDM6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-C2H2~zf-C2H2
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0005634 - nucleus
GO:0032259 - methylation
GO:0046872 - metal ion binding
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 571
Hs

1 595
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Last updated: 15 Jul 2024