HitPredict

Interactor 1: UBA5 (Q9GZZ9)
Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5) (ThiFP1) (UFM1-activating enzyme) (Ubiquitin-activating enzyme E1 domain-containing protein 1)
Gene: UBA5

Interactor 2: HERC5 (Q9UII4)
E3 ISG15--protein ligase HERC5 (EC 2.3.2.-) (Cyclin-E-binding protein 1) (HECT domain and RCC1-like domain-containing protein 5)
Gene: HERC5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35671810
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 404 Hs			1 1024
+	Hs
		313159 MOCS3_HUMAN (1-292): 8.71e-73: 236: 24.41		HERC5_HUMAN (1-1024): 0: 1123: 100.00
+	Hs
		1252665 UBA3_HUMAN (6-247): 2.13e-65: 217: 19.77		HERC5_HUMAN (1-1024): 0: 1123: 100.00
+	Hs
		311775 ATG7_HUMAN (19-351): 3.67e-60: 208: 13.69		HERC5_HUMAN (1-1024): 0: 1123: 100.00
+	Hs
		1354311 SAE2_HUMAN (57-233): 2.97e-53: 189: 26.40		HERC5_HUMAN (1-1024): 0: 1123: 100.00
+	Hs
		607185 UBA1_HUMAN (20-218): 5.28e-32: 130: 13.15		HERC5_HUMAN (1-1024): 0: 1123: 100.00
+	Hs
		983261 SAE2_HUMAN (57-233): 2.97e-53: 189: 26.40		UBE3A_HUMAN (414-1024): 1.12e-172: 529: 25.37
+	Hs
		125155 UBA1_HUMAN (20-218): 5.28e-32: 130: 13.15		WWP2_HUMAN (599-1024): 1.14e-167: 516: 22.02
+	Hs
		607135 UBA1_HUMAN (20-218): 5.28e-32: 130: 13.15		ITCH_HUMAN (593-1024): 1.76e-165: 511: 24.22
+	Hs
		313135 MOCS3_HUMAN (1-292): 8.71e-73: 236: 24.41		HERC4_HUMAN (317-431): 2.55e-13: 76.6: 11.02