HitPredict

Interactor 1: SDCB1 (O00560)
Syntenin-1 (Melanoma differentiation-associated protein 9) (MDA-9) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18) (Scaffold protein Pbp1) (Syndecan-binding protein 1)
Gene: SDCBP

Interactor 2: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005886 - plasma membrane GO:0005925 - focal adhesion and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 298 Hs			1 192
+	Hs
		132816 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19
+	Hs
		132739 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03
+	Hs
		132804 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01
+	Hs
		132805 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75
+	Hs
		132808 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26
+	Hs
		132717 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		RHOC_HUMAN (5-192): 1.83e-73: 221: 54.79
+	Hs
		925382 PREX2_HUMAN (108-256): 2.7e-39: 148: 20.40		RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19
+	Hs
		951099 PREX2_HUMAN (108-256): 2.7e-39: 148: 20.40		RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83
+	Hs
		894155 PREX2_HUMAN (108-256): 2.7e-39: 148: 20.40		CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75
+	Hs
		900616 PREX2_HUMAN (108-256): 2.7e-39: 148: 20.40		RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26
+	Mm
		925797 DLG4_MOUSE (193-286): 2.27e-16: 81.4: 24.75		RAC1_MOUSE (1-192): 1.69e-84: 249: 92.19
+	Hs
		564636 DLG3_HUMAN (184-268): 1.4e-17: 84.8: 26.09		RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03
+	Hs
		564526 SCRIB_HUMAN (161-276): 6.09e-16: 80.2: 18.61		RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03
+	Hs
		545370 SCRIB_HUMAN (161-276): 6.09e-16: 80.2: 18.61		RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00
+	Mm
		1111996 DLG4_MOUSE (193-286): 2.27e-16: 81.4: 24.75		Q3TLP8_MOUSE (1-192): 5.9e-80: 238: 83.41
+	Hs
		892525 DLG3_HUMAN (184-268): 1.4e-17: 84.8: 26.09		RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01
+	Hs
		951207 DLG3_HUMAN (184-268): 1.4e-17: 84.8: 26.09		RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83
+	Hs
		892367 SCRIB_HUMAN (161-276): 6.09e-16: 80.2: 18.61		RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01
+	Hs
		900762 DLG3_HUMAN (184-268): 1.4e-17: 84.8: 26.09		RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26
+	Hs
		436297 SCRIB_HUMAN (161-276): 6.09e-16: 80.2: 18.61		RHOC_HUMAN (5-192): 1.83e-73: 221: 54.79