Protein: PER2
Period circadian protein homolog 2 (mPER2) (Circadian clock protein PERIOD 2)

Gene: PER2
Organism: Mus musculus
Interactions: 37
UniProt ID: O54943

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001222 - transcription corepressor binding
GO:0002931 - response to ischemia

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

236749

CRY1
Cryptochrome-1

11

20

Small-scale

0.978

High

236769

CRY2
Cryptochrome-2

9

20

Small-scale

0.965

High

148267

CLOCK
Circadian locomoter output cycles protein kaput

8

19

Small-scale

0.960

High

236771

BMAL1
Basic helix-loop-helix ARNT-like protein 1

8

18

Small-scale

0.957

High

236742

PER2
Period circadian protein homolog 2

4

19

Small-scale

0.910

High

205739

PER1
Period circadian protein homolog 1

4

18

Small-scale

0.860

High

236743

PER3
Period circadian protein homolog 3

2

19

Small-scale

0.743

High

236768

KC1E
Casein kinase I isoform epsilon

6

20

Small-scale

0.720

High

236751

FBW1A
F-box/WD repeat-containing protein 1A

3

13

Small-scale

0.656

High

236766

KC1D
Casein kinase I isoform delta

3

20

Small-scale

0.633

High

236770

TIM
Protein timeless homolog

2

4

Small-scale

0.595

High

236762

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

9

Small-scale

0.586

High

236752

NR1D1
Nuclear receptor subfamily 1 group D member 1

2

20

Small-scale

0.584

High

236759

FBXL3
F-box/LRR-repeat protein 3

2

1

Small-scale

0.584

High

236746

CDK5
Cyclin-dependent kinase 5

1

2

Small-scale

0.578

High

236747

FOXP1
Forkhead box protein P1

1

12

High-throughput

0.541

High

236761

CAVN3
Caveolae-associated protein 3

1

3

Small-scale

0.536

High

236764

TF2AA
Transcription initiation factor IIA subunit 1

1

0

High-throughput

0.518

High

236754

PML
Protein PML

1

12

Small-scale

0.515

High

148628

HDAC1
Histone deacetylase 1

1

11

Small-scale

0.500

High

236509

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

3

Small-scale

0.500

High

236745

CBX3
Chromobox protein homolog 3

1

4

Small-scale

0.500

High

236755

TIF1B
Transcription intermediary factor 1-beta

1

17

Small-scale

0.500

High

236767

SUV92
Histone-lysine N-methyltransferase SUV39H2

1

3

Small-scale

0.500

High

236756

MED16
Mediator of RNA polymerase II transcription subunit 16

1

2

High-throughput

0.481

High

236744

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

11

Small-scale

0.479

High

236748

MK01
Mitogen-activated protein kinase 1

1

4

Small-scale

0.479

High

236750

CIART
Circadian-associated transcriptional repressor

1

2

Small-scale

0.479

High

236753

SIN3A
Paired amphipathic helix protein Sin3a

1

3

Small-scale

0.479

High

236757

FXL21
F-box/LRR-repeat protein 21

1

1

Small-scale

0.479

High

236758

KC1A
Casein kinase I isoform alpha

1

20

Small-scale

0.479

High

236760

SFPQ
Splicing factor, proline- and glutamine-rich

1

7

Small-scale

0.479

High

236763

NONO
Non-POU domain-containing octamer-binding protein

1

8

Small-scale

0.479

High

236765

BHE41
Class E basic helix-loop-helix protein 41

1

7

High-throughput

0.457

High

236344

CAVN1
Caveolae-associated protein 1

1

3

Small-scale

0.445

High

107943

G3UW74
Mediator of RNA polymerase II transcription subunit 16

1

2

High-throughput

0.417

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025