HitPredict

Interactor 1: LRC52 (Q8N7C0)
Leucine-rich repeat-containing protein 52 (BK channel auxiliary gamma subunit LRRC52)
Gene: LRRC52

Interactor 2: LRRC3 (Q9BY71)
Leucine-rich repeat-containing protein 3
Gene: LRRC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LRR_1~LRR_8, LRR_8~LRR_8, LRRNT~LRR_8
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 313 Hs			1 257
+	Dm
		1467073 Q9V9V6_DROME (9-236): 1.2e-52: 186: 22.61		Q9VKG1_DROME (17-198): 3.13e-35: 135: 26.34
+	Dm
		1479594 Q9VWI6_DROME (24-248): 8.06e-47: 170: 25.10		Q9VKG1_DROME (17-198): 3.13e-35: 135: 26.34
+	Dm
		1479139 Q9VK54_DROME (24-277): 3.33e-45: 165: 20.78		Q9VKG1_DROME (17-198): 3.13e-35: 135: 26.34
+	At
		1192477 ERECT_ARATH (1-275): 7.52e-39: 147: 16.13		TMM_ARATH (2-238): 5.06e-34: 129: 17.07
+	Hs
		1438476 LRRC4_HUMAN (22-278): 4.67e-54: 188: 21.67		LRC4C_HUMAN (2-170): 2.09e-18: 86: 17.32
+	Hs
		1439140 LRC4B_HUMAN (15-239): 3.18e-53: 187: 22.98		LRC4C_HUMAN (2-170): 2.09e-18: 86: 17.32
+	At
		88649 RGI3_ARATH (1-232): 3.43e-39: 148: 17.30		GSO1_ARATH (2-252): 1.16e-31: 124: 15.33
+	At
		88667 ERECT_ARATH (1-275): 7.52e-39: 147: 16.13		GSO1_ARATH (2-252): 1.16e-31: 124: 15.33
+	Hs
		1453617 FLRT1_HUMAN (4-234): 8.7e-45: 163: 21.85		FLRT3_HUMAN (41-191): 2.11e-22: 97.6: 19.50
+	Mm
		1297649 ELFN1_MOUSE (4-226): 2.41e-48: 174: 25.64		LRC4C_MOUSE (2-170): 2.44e-18: 86: 17.32
+	At
		1192463 ERECT_ARATH (1-275): 7.52e-39: 147: 16.13		FLS2_ARATH (10-253): 1.4e-26: 110: 13.59
+	At
		88662 GSO1_ARATH (1-271): 1.17e-38: 147: 14.49		SKM1_ARATH (2-180): 9.05e-27: 110: 14.97
+	At
		1192484 ERECT_ARATH (1-275): 7.52e-39: 147: 16.13		BRL1_ARATH (31-257): 7.47e-26: 107: 15.23
+	At
		1442339 Y1571_ARATH (9-310): 7.5e-42: 156: 18.07		BRL2_ARATH (2-193): 3.73e-22: 97.2: 12.60
+	Dr
		85873 Q6WZD2_DANRE (6-244): 1.03e-53: 184: 21.22		B8JKM0_DANRE (42-209): 1.11e-12: 69.1: 16.07
+	Mm
		1229343 PPR29_MOUSE (39-231): 6.51e-46: 167: 27.69		LRC4C_MOUSE (2-170): 2.44e-18: 86: 17.32
+	At
		88535 Y1571_ARATH (9-310): 7.5e-42: 156: 18.07		Y3148_ARATH (2-168): 1.52e-20: 92.5: 11.62
+	Zm
		19535 A0A1D6HD42_MAIZE (27-306): 4.16e-40: 151: 16.55		A0A1D6HD42_MAIZE (2-158): 1.05e-19: 90.2: 18.75
+	At
		88506 GSO1_ARATH (1-271): 1.17e-38: 147: 14.49		Y3148_ARATH (2-168): 1.52e-20: 92.5: 11.62
+	Dr
		98306 E9QDQ3_DANRE (2-224): 8.99e-41: 153: 25.99		E9QDQ3_DANRE (7-148): 3.55e-17: 82.5: 18.06