HitPredict

Interactor 1: CHM4B (Q9H444)
Charged multivesicular body protein 4b (Chromatin-modifying protein 4b) (CHMP4b) (SNF7 homolog associated with Alix 1) (SNF7-2) (hSnf7-2) (Vacuolar protein sorting-associated protein 32-2) (Vps32-2) (hVps32-2)
Gene: CHMP4B

Interactor 2: CHMP3 (Q9Y3E7)
Charged multivesicular body protein 3 (Chromatin-modifying protein 3) (Neuroendocrine differentiation factor) (Vacuolar protein sorting-associated protein 24) (hVps24)
Gene: CHMP3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 16730941, 26496610, 23051622
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, surface plasmon resonance
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Snf7~Snf7
Common GO terms GO:0000421 - autophagosome membrane
GO:0000776 - kinetochore
GO:0000815 - ESCRT III complex
GO:0001778 - plasma membrane repair
GO:0005643 - nuclear pore
and 29 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 224
Hs

1 222
+ Ce
+ Hs
+ Hs
+ At
+ At
+ Ce
+ At
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024