HitPredict

Interactor 1: SAV1 (Q9H4B6)
Protein salvador homolog 1 (45 kDa WW domain protein) (hWW45)
Gene: SAV1

Interactor 2: RASF1 (Q9NS23)
Ras association domain-containing protein 1
Gene: RASSF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.690

Property	Details
Experiments	24981860, 17379520, 21489991, 20920251
Identification Methods	affinity chromatography technology, pull down, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0050821 - protein stabilization
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 383 Hs			1 344
+	Hs
		1262936 SAV1_HUMAN (1-383): 9.28e-111: 330: 100.00		RASF5_HUMAN (11-339): 8.08e-111: 330: 43.23
+	Hs
		1336090 SMUF1_HUMAN (147-381): 2.43e-59: 206: 18.32		RASF1_HUMAN (1-344): 7.96e-150: 427: 100.00
+	Hs
		1294869 ITCH_HUMAN (41-315): 8.61e-36: 141: 19.36		RASF1_HUMAN (1-344): 7.96e-150: 427: 100.00
+	Hs
		841565 SAV1_HUMAN (1-383): 9.28e-111: 330: 100.00		RASF2_HUMAN (122-339): 1.48e-67: 217: 23.61
+	Hs
		1172536 SAV1_HUMAN (1-383): 9.28e-111: 330: 100.00		RASF6_HUMAN (134-339): 1.28e-65: 213: 22.73
+	Hs
		1203195 SAV1_HUMAN (1-383): 9.28e-111: 330: 100.00		RASF3_HUMAN (118-339): 2.62e-59: 192: 44.44
+	Hs
		1329566 SAV1_HUMAN (1-383): 9.28e-111: 330: 100.00		RASF4_HUMAN (117-339): 4.8e-51: 173: 24.17
+	Hs
		1262928 ITCH_HUMAN (41-315): 8.61e-36: 141: 19.36		RASF5_HUMAN (11-339): 8.08e-111: 330: 43.23
+	Hs
		397181 SMUF1_HUMAN (147-381): 2.43e-59: 206: 18.32		KPCG_HUMAN (24-277): 2.91e-54: 190: 17.47
+	Hs
		566484 SMUF1_HUMAN (147-381): 2.43e-59: 206: 18.32		KPCA_HUMAN (24-266): 3.82e-36: 140: 12.74
+	Dm
		1363056 SAV_DROME (81-373): 5.46e-33: 131: 32.12		Q9VCQ7_DROME (100-340): 7.44e-55: 193: 20.62
+	Hs
		566415 WWC2_HUMAN (190-383): 1.85e-37: 146: 20.29		KPCA_HUMAN (24-266): 3.82e-36: 140: 12.74
+	Hs
		566424 KIBRA_HUMAN (197-355): 2.75e-30: 124: 20.47		KPCA_HUMAN (24-266): 3.82e-36: 140: 12.74
+	Hs
		566492 WWOX_HUMAN (198-282): 3.98e-30: 121: 31.87		KPCA_HUMAN (24-266): 3.82e-36: 140: 12.74
+	Hs
		983870 KIBRA_HUMAN (197-355): 2.75e-30: 124: 20.47		KPCZ_HUMAN (15-152): 6.03e-34: 133: 24.11
+	Hs
		566504 WWC3_HUMAN (194-265): 4.37e-26: 112: 40.48		KPCA_HUMAN (24-266): 3.82e-36: 140: 12.74