HitPredict

Interactor 1: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Interactor 2: RAB6B (Q9NRW1)
Ras-related protein Rab-6B (EC 3.6.5.2)
Gene: RAB6B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 779 Hs			1 208
+	Hs
		592495 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		RAB5A_HUMAN (3-207): 4.67e-89: 262: 40.78
+	Hs
		844738 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		RAB5C_HUMAN (3-207): 3.56e-89: 262: 40.98
+	Hs
		918949 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		RAB1A_HUMAN (1-207): 7.26e-89: 261: 34.30
+	Hs
		1328144 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		RAB1B_HUMAN (7-206): 1.58e-87: 258: 35.50
+	Hs
		592704 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		RAB6A_HUMAN (1-208): 1.37e-84: 250: 90.87
+	Hs
		914357 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		RB11A_HUMAN (7-206): 6.52e-84: 249: 28.71
+	Hs
		895380 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		RAB5B_HUMAN (13-178): 5.66e-49: 160: 45.78
+	Hs
		895273 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		RAB2A_HUMAN (14-191): 5.16e-45: 150: 39.89
+	Hs
		1044488 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		RAB31_HUMAN (11-196): 5.59e-45: 149: 36.56
+	Hs
		592584 TBD2B_HUMAN (53-512): 3.31e-51: 195: 17.57		RAB5A_HUMAN (3-207): 4.67e-89: 262: 40.78
+	Hs
		914051 GAB1_HUMAN (52-611): 6.48e-53: 197: 13.92		RB11A_HUMAN (7-206): 6.52e-84: 249: 28.71
+	Hs
		914465 TBD2B_HUMAN (53-512): 3.31e-51: 195: 17.57		RB11A_HUMAN (7-206): 6.52e-84: 249: 28.71
+	Hs
		592656 TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28		RAB6A_HUMAN (1-208): 1.37e-84: 250: 90.87
+	Hs
		914432 SWP70_HUMAN (55-446): 3.06e-44: 170: 11.36		RB11A_HUMAN (7-206): 6.52e-84: 249: 28.71
+	Hs
		592263 ACAP2_HUMAN (28-517): 6.24e-39: 156: 13.10		RAB5A_HUMAN (3-207): 4.67e-89: 262: 40.78
+	Ce
		1095338 Q23419_CAEEL (46-578): 5.81e-41: 163: 12.59		RAB10_CAEEL (9-206): 2.33e-85: 252: 37.37
+	Hs
		592506 PKHA1_HUMAN (16-261): 3.76e-39: 151: 16.92		RAB5A_HUMAN (3-207): 4.67e-89: 262: 40.78
+	Hs
		914370 PKHA1_HUMAN (16-261): 3.76e-39: 151: 16.92		RB11A_HUMAN (7-206): 6.52e-84: 249: 28.71
+	Hs
		895058 TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28		RAB2A_HUMAN (14-191): 5.16e-45: 150: 39.89
+	Hs
		895119 RHG21_HUMAN (22-662): 1.96e-43: 172: 13.18		RAB2A_HUMAN (14-191): 5.16e-45: 150: 39.89