HitPredict

Interactor 1: GBB4 (Q9HAV0)
Guanine nucleotide-binding protein subunit beta-4 (Transducin beta chain 4)
Gene: GNB4

Interactor 2: NR2E1 (Q9Y466)
Nuclear receptor subfamily 2 group E member 1 (Nuclear receptor TLX) (Protein tailless homolog) (Tll) (hTll)
Gene: NR2E1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	26186194
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 340 Hs			1 385
+	Hs
		369344 GBB2_HUMAN (1-340): 1.05e-110: 327: 90.00		ESR1_HUMAN (8-385): 6.09e-98: 305: 29.06
+	Hs
		370470 GBB4_HUMAN (1-340): 1.76e-110: 326: 100.00		ESR1_HUMAN (8-385): 6.09e-98: 305: 29.06
+	Hs
		369342 GBB1_HUMAN (1-340): 1.71e-106: 316: 90.88		ESR1_HUMAN (8-385): 6.09e-98: 305: 29.06
+	Hs
		320198 GBB2_HUMAN (1-340): 1.05e-110: 327: 90.00		ERR2_HUMAN (11-383): 7.04e-92: 284: 28.95
+	Hs
		320228 GBB4_HUMAN (1-340): 1.76e-110: 326: 100.00		ERR2_HUMAN (11-383): 7.04e-92: 284: 28.95
+	Hs
		320197 GBB1_HUMAN (1-340): 1.71e-106: 316: 90.88		ERR2_HUMAN (11-383): 7.04e-92: 284: 28.95
+	Hs
		921671 GBB2_HUMAN (1-340): 1.05e-110: 327: 90.00		ESR2_HUMAN (2-382): 4.9e-86: 272: 26.75
+	Hs
		320167 GBB3_HUMAN (1-340): 1.25e-105: 314: 79.71		ERR2_HUMAN (11-383): 7.04e-92: 284: 28.95
+	Hs
		921023 GBB1_HUMAN (1-340): 1.71e-106: 316: 90.88		ESR2_HUMAN (2-382): 4.9e-86: 272: 26.75
+	Hs
		560885 GBB3_HUMAN (1-340): 1.25e-105: 314: 79.71		ESR2_HUMAN (2-382): 4.9e-86: 272: 26.75
+	Hs
		369932 WDR5B_HUMAN (3-211): 8.6e-58: 191: 20.91		ESR1_HUMAN (8-385): 6.09e-98: 305: 29.06
+	Hs
		488008 SNR40_HUMAN (130-340): 1.94e-58: 194: 24.77		RARA_HUMAN (14-384): 1.47e-89: 279: 25.34
+	Hs
		1269746 NLE1_HUMAN (3-124): 3.15e-32: 127: 25.40		ESR2_HUMAN (2-382): 4.9e-86: 272: 26.75
+	Hs
		369305 WDR5_HUMAN (263-340): 5.61e-19: 88.1: 23.08		ESR1_HUMAN (8-385): 6.09e-98: 305: 29.06
+	Hs
		782513 WDR5_HUMAN (263-340): 5.61e-19: 88.1: 23.08		HNF4A_HUMAN (2-383): 6.31e-98: 301: 30.16
+	Hs
		903650 WDR5_HUMAN (263-340): 5.61e-19: 88.1: 23.08		NR2E3_HUMAN (8-382): 2.3e-96: 295: 42.78
+	Hs
		196938 PRP4_HUMAN (51-253): 3.65e-11: 65.9: 24.88		ESR1_HUMAN (8-385): 6.09e-98: 305: 29.06
+	Mm
		903664 WDR5_MOUSE (263-340): 5.61e-19: 88.1: 23.08		ERR2_MOUSE (11-383): 4.3e-90: 279: 28.95
+	Hs
		903403 WDR5_HUMAN (263-340): 5.61e-19: 88.1: 23.08		ESR2_HUMAN (2-382): 4.9e-86: 272: 26.75
+	Hs
		154683 GNB5_HUMAN (129-340): 9.12e-43: 154: 23.08		NR6A1_HUMAN (16-375): 2.59e-33: 131: 25.82