Protein: ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (MCAD) (EC 1.3.8.7) (Medium chain acyl-CoA dehydrogenase) (MCADH)

Gene: ACADM
Organism: Homo sapiens
Interactions: 94
UniProt ID: P11310

Gene Ontology (top 5):
GO:0001889 - liver development
GO:0003995 - acyl-CoA dehydrogenase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

541074

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

2

14

Small-scale

0.792

High

541102

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

3

4

Small-scale

0.640

High

541126

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

14

High-throughput

0.618

High

541081

ETFB
Electron transfer flavoprotein subunit beta

1

3

Small-scale

0.575

High

541114

AURKB
Aurora kinase B

2

3

High-throughput

0.571

High

541080

MYH9
Myosin-9

1

1

High-throughput

0.536

High

541096

HDAC1
Histone deacetylase 1

1

2

High-throughput

0.536

High

541097

CUL3
Cullin-3

1

2

High-throughput

0.536

High

541139

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

1

High-throughput

0.536

High

369010

ASSY
Argininosuccinate synthase

1

0

High-throughput

0.513

High

480667

LEG1
Galectin-1

1

0

High-throughput

0.513

High

541077

BLVRB
Flavin reductase

1

0

High-throughput

0.513

High

541092

AKA12
A-kinase anchor protein 12

1

0

High-throughput

0.513

High

541105

UBP50
Ubiquitin carboxyl-terminal hydrolase 50

1

0

High-throughput

0.513

High

541108

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.513

High

541129

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.513

High

541089

CDC42
Cell division control protein 42 homolog

1

5

High-throughput

0.501

High

541109

PNKD
Probable thioesterase PNKD

1

0

High-throughput

0.493

High

541099

P2RY6
P2Y purinoceptor 6

1

4

High-throughput

0.489

High

541119

TX101
Testis-expressed protein 101

1

2

High-throughput

0.489

High

541140

SAR1B
Small COPII coat GTPase SAR1B

1

3

High-throughput

0.489

High

156590

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

4

High-throughput

0.481

High

240592

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

279630

CISY
Citrate synthase, mitochondrial

1

6

High-throughput

0.479

High

281866

MPPB
Mitochondrial-processing peptidase subunit beta

1

8

High-throughput

0.479

High

293118

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.479

High

330612

KI20A
Kinesin-like protein KIF20A

1

4

High-throughput

0.479

High

350775

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

4

High-throughput

0.479

High

411259

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.479

High

470825

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

6

High-throughput

0.479

High

519035

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

3

High-throughput

0.479

High

532316

CH60
60 kDa heat shock protein, mitochondrial

1

4

High-throughput

0.479

High

541075

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

541082

MDHM
Malate dehydrogenase, mitochondrial

1

7

High-throughput

0.479

High

541083

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

541084

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

2

High-throughput

0.479

High

541085

EFTS
Elongation factor Ts, mitochondrial

1

4

High-throughput

0.479

High

541086

RECQ1
ATP-dependent DNA helicase Q1

1

1

High-throughput

0.479

High

541091

KIF23
Kinesin-like protein KIF23

1

2

High-throughput

0.479

High

541094

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

2

High-throughput

0.479

High

541098

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

541100

PDK1
[Pyruvate dehydrogenase

1

6

High-throughput

0.479

High

541101

E2F4
Transcription factor E2F4

1

2

High-throughput

0.479

High

541103

MRM1
rRNA methyltransferase 1, mitochondrial

1

3

High-throughput

0.479

High

541104

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.479

High

541110

SERB1
SERPINE1 mRNA-binding protein 1

1

2

High-throughput

0.479

High

541112

MCUR1
Mitochondrial calcium uniporter regulator 1

1

4

High-throughput

0.479

High

541116

CI072
Guanine nucleotide exchange factor C9orf72

1

2

High-throughput

0.479

High

541117

IMP2L
Mitochondrial inner membrane protease subunit 2

1

6

High-throughput

0.479

High

541118

TR61B
tRNA

1

3

High-throughput

0.479

High

541120

RT26
Small ribosomal subunit protein mS26

1

2

High-throughput

0.479

High

541123

MTRFR
Mitochondrial translation release factor in rescue

1

6

High-throughput

0.479

High

541124

MTG2
Mitochondrial ribosome-associated GTPase 2

1

8

High-throughput

0.479

High

541125

MET17
Ribosome assembly protein METTL17, mitochondrial

1

4

High-throughput

0.479

High

541127

BRD7
Bromodomain-containing protein 7

1

6

High-throughput

0.479

High

541132

TLS1
Splicing factor C9orf78

1

3

High-throughput

0.479

High

541133

MRES1
Mitochondrial transcription rescue factor 1

1

2

High-throughput

0.479

High

541134

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

6

High-throughput

0.479

High

541135

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

541111

PANK1
Pantothenate kinase 1

1

0

High-throughput

0.460

High

319341

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

325659

UBR5
E3 ubiquitin-protein ligase UBR5

1

0

Small-scale

0.458

High

413078

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

415304

HSPB1
Heat shock protein beta-1

1

0

Small-scale

0.458

High

541078

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.458

High

541090

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.458

High

541093

MECOM
Histone-lysine N-methyltransferase MECOM

1

0

High-throughput

0.458

High

541106

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

541115

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

541130

INKA2
PAK4-inhibitor INKA2

1

0

Small-scale

0.458

High

541136

UBQL2
Ubiquilin-2

1

0

High-throughput

0.458

High

541138

FND3A
Fibronectin type-III domain-containing protein 3A

1

0

High-throughput

0.458

High

902

SIM26
Small integral membrane protein 26

1

1

High-throughput

0.445

High

429199

JUN
Transcription factor Jun

1

2

High-throughput

0.445

High

540980

PIM1
Serine/threonine-protein kinase pim-1

1

3

High-throughput

0.445

High

541076

HEMH
Ferrochelatase, mitochondrial

1

2

High-throughput

0.445

High

541088

NCBP2
Nuclear cap-binding protein subunit 2

1

2

High-throughput

0.445

High

541095

RM49
Large ribosomal subunit protein mL49

1

2

High-throughput

0.445

High

156890

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.437

High

541079

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

541087

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.437

High

541113

FAF2
FAS-associated factor 2

1

3

High-throughput

0.437

High

541128

ANLN
Anillin

1

1

High-throughput

0.437

High

397885

ANGI
Angiogenin

1

0

High-throughput

0.426

High

541122

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

1

High-throughput

0.407

High

541137

ITM2B
Integral membrane protein 2B

1

3

High-throughput

0.407

High

184106

RER1
Protein RER1

1

0

High-throughput

0.279

Low

209456

SERA
D-3-phosphoglycerate dehydrogenase

1

0

High-throughput

0.279

Low

532203

ESTD
S-formylglutathione hydrolase

1

0

High-throughput

0.279

Low

541107

HEAT3
HEAT repeat-containing protein 3

1

0

High-throughput

0.279

Low

541131

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

0

High-throughput

0.279

Low

330025

VENTX
Homeobox protein VENTX

1

0

High-throughput

0.232

Low

541121

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025