Protein: K1C16
Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)

Gene: K1C16, KRT16
Organism: Homo sapiens
Interactions: 187
UniProt ID: P08779

Gene Ontology (top 5):
GO:0001533 - cornified envelope
GO:0002009 - morphogenesis of an epithelium
GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

213927

KRT86
Keratin, type II cuticular Hb6

2

20

High-throughput

0.783

High

359454

K2C6A
Keratin, type II cytoskeletal 6A

2

20

High-throughput

0.783

High

380539

K2C1
Keratin, type II cytoskeletal 1

2

20

High-throughput

0.783

High

408981

K2C8
Keratin, type II cytoskeletal 8

2

20

High-throughput

0.783

High

444997

K2C3
Keratin, type II cytoskeletal 3

2

20

High-throughput

0.783

High

445000

K2C5
Keratin, type II cytoskeletal 5

2

20

High-throughput

0.783

High

445010

K22E
Keratin, type II cytoskeletal 2 epidermal

2

20

High-throughput

0.783

High

445013

PERI
Peripherin

2

20

High-throughput

0.783

High

445017

K2C6C
Keratin, type II cytoskeletal 6C

2

20

High-throughput

0.783

High

445028

KRT83
Keratin, type II cuticular Hb3

2

20

High-throughput

0.783

High

445029

KRT85
Keratin, type II cuticular Hb5

2

20

High-throughput

0.783

High

445033

K22O
Keratin, type II cytoskeletal 2 oral

2

20

High-throughput

0.783

High

445046

KRT81
Keratin, type II cuticular Hb1

2

20

High-throughput

0.783

High

445048

K2C72
Keratin, type II cytoskeletal 72

2

20

High-throughput

0.783

High

445061

K2C71
Keratin, type II cytoskeletal 71

2

20

High-throughput

0.783

High

445068

K2C79
Keratin, type II cytoskeletal 79

2

20

High-throughput

0.783

High

445070

K2C80
Keratin, type II cytoskeletal 80

2

20

High-throughput

0.783

High

445078

K2C74
Keratin, type II cytoskeletal 74

2

20

High-throughput

0.783

High

445082

K2C73
Keratin, type II cytoskeletal 73

2

20

High-throughput

0.783

High

445086

K2C78
Keratin, type II cytoskeletal 78

2

20

High-throughput

0.783

High

422329

NFM
Neurofilament medium polypeptide

1

20

High-throughput

0.691

High

445056

AINX
Alpha-internexin

1

20

High-throughput

0.691

High

445123

SYNCI
Syncoilin

1

20

High-throughput

0.691

High

445002

K2C4
Keratin, type II cytoskeletal 4

1

20

High-throughput

0.665

High

445110

TCHP
Trichoplein keratin filament-binding protein

3

16

Small-scale

0.663

High

318770

K2C75
Keratin, type II cytoskeletal 75

1

20

High-throughput

0.621

High

380438

K2C6B
Keratin, type II cytoskeletal 6B

1

20

High-throughput

0.621

High

445079

K2C1B
Keratin, type II cytoskeletal 1b

1

20

High-throughput

0.621

High

445129

KRT82
Keratin, type II cuticular Hb2

1

20

High-throughput

0.621

High

445035

K1C17
Keratin, type I cytoskeletal 17

1

20

High-throughput

0.618

High

445104

SGF29
SAGA-associated factor 29

3

7

High-throughput

0.607

High

159854

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

17

High-throughput

0.606

High

310891

SNAPN
SNARE-associated protein Snapin

2

6

High-throughput

0.606

High

328476

MBD3
Methyl-CpG-binding domain protein 3

2

4

High-throughput

0.606

High

330055

DRC4
Dynein regulatory complex subunit 4

2

4

High-throughput

0.606

High

445006

CCNC
Cyclin-C

2

8

High-throughput

0.606

High

445007

RBTN1
Rhombotin-1

2

15

High-throughput

0.606

High

445021

ARFP2
Arfaptin-2

2

5

High-throughput

0.606

High

445022

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

2

2

High-throughput

0.606

High

445036

CDK18
Cyclin-dependent kinase 18

2

5

High-throughput

0.606

High

445057

PKN1
Serine/threonine-protein kinase N1

2

11

High-throughput

0.606

High

445060

PUS10
tRNA pseudouridine synthase Pus10

2

1

High-throughput

0.606

High

445071

PPR18
Phostensin

2

9

High-throughput

0.606

High

445077

EPMIP
EPM2A-interacting protein 1

2

2

High-throughput

0.606

High

445085

CC146
Coiled-coil domain-containing protein 146

2

11

High-throughput

0.606

High

445093

CCHCR
Coiled-coil alpha-helical rod protein 1

2

17

High-throughput

0.606

High

445099

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

2

8

High-throughput

0.606

High

445105

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

2

5

High-throughput

0.606

High

445109

TS101
Tumor susceptibility gene 101 protein

2

7

High-throughput

0.606

High

445112

KIFC3
Kinesin-like protein KIFC3

2

14

High-throughput

0.606

High

445121

CARD9
Caspase recruitment domain-containing protein 9

2

10

High-throughput

0.606

High

445132

AIRIM
AFG2-interacting ribosome maturation factor

2

6

High-throughput

0.606

High

445138

DPOLL
DNA polymerase lambda

2

2

High-throughput

0.606

High

445139

CYH4
Cytohesin-4

2

5

High-throughput

0.606

High

445018

GBG10

2

5

High-throughput

0.553

High

445067

TTC23
Tetratricopeptide repeat protein 23

2

13

High-throughput

0.553

High

445088

TXLNB
Beta-taxilin

2

20

High-throughput

0.553

High

445090

USBP1
Harmonin-binding protein USHBP1

2

14

High-throughput

0.553

High

445091

CA216
UPF0500 protein C1orf216

2

9

High-throughput

0.553

High

445092

LNX1
E3 ubiquitin-protein ligase LNX

2

9

High-throughput

0.553

High

445107

CCD17
Coiled-coil domain-containing protein 17

2

1

High-throughput

0.553

High

445115

SEM4C
Semaphorin-4C

2

3

High-throughput

0.553

High

445130

KLC4
Kinesin light chain 4

2

16

High-throughput

0.553

High

363696

ALBU
Albumin

1

7

High-throughput

0.536

High

444998

CFTR
Cystic fibrosis transmembrane conductance regulator

1

20

High-throughput

0.536

High

445011

IF4A3
Eukaryotic initiation factor 4A-III

1

16

High-throughput

0.536

High

445012

TXLNA
Alpha-taxilin

1

20

High-throughput

0.536

High

445040

CUL1
Cullin-1

1

20

High-throughput

0.536

High

445041

CUL2
Cullin-2

1

20

High-throughput

0.536

High

445042

CUL3
Cullin-3

1

20

High-throughput

0.536

High

445043

CUL4B
Cullin-4B

1

20

High-throughput

0.536

High

445049

FL2D
Pre-mRNA-splicing regulator WTAP

1

8

High-throughput

0.536

High

445052

PLEC
Plectin

1

20

High-throughput

0.536

High

445053

PCM1
Pericentriolar material 1 protein

1

7

High-throughput

0.536

High

445054

NEDD8
NEDD8

1

6

High-throughput

0.536

High

445058

MK06
Mitogen-activated protein kinase 6

1

2

High-throughput

0.536

High

445080

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

12

High-throughput

0.536

High

445081

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

7

High-throughput

0.536

High

445084

AMOL1
Angiomotin-like protein 1

1

20

High-throughput

0.536

High

445097

CSN5
COP9 signalosome complex subunit 5

1

17

High-throughput

0.536

High

445111

FSD1
Fibronectin type III and SPRY domain-containing protein 1

1

20

High-throughput

0.536

High

445122

GAN
Gigaxonin

1

12

High-throughput

0.536

High

445126

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

12

High-throughput

0.536

High

445131

TXLNG
Gamma-taxilin

1

20

High-throughput

0.536

High

445133

CACO1
Calcium-binding and coiled-coil domain-containing protein 1

1

8

High-throughput

0.536

High

445143

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

4

High-throughput

0.536

High

361302

APOA1
Apolipoprotein A-I

1

0

High-throughput

0.513

High

445059

KIF7
Kinesin-like protein KIF7

1

3

High-throughput

0.489

High

445032

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

10

High-throughput

0.484

High

445063

AMOT
Angiomotin

1

20

High-throughput

0.481

High

124736

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

9

Small-scale

0.479

High

129174

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

20

High-throughput

0.479

High

133848

DDX3X
ATP-dependent RNA helicase DDX3X

1

7

Small-scale

0.479

High

176354

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

11

High-throughput

0.479

High

197194

SERA
D-3-phosphoglycerate dehydrogenase

1

7

Small-scale

0.479

High

226314

PRKN
E3 ubiquitin-protein ligase parkin

1

15

High-throughput

0.479

High

255446

OBSL1
Obscurin-like protein 1

1

9

High-throughput

0.479

High

260460

PITX3
Pituitary homeobox 3

1

9

Small-scale

0.479

High

277891

PIAS1
E3 SUMO-protein ligase PIAS1

1

3

High-throughput

0.479

High

282490

RNF8
E3 ubiquitin-protein ligase RNF8

1

15

High-throughput

0.479

High

302812

HEXI1
Protein HEXIM1

1

20

High-throughput

0.479

High

325601

LATS1
Serine/threonine-protein kinase LATS1

1

11

High-throughput

0.479

High

337809

EGFR
Epidermal growth factor receptor

1

11

High-throughput

0.479

High

345743

MYC
Myc proto-oncogene protein

1

13

High-throughput

0.479

High

362721

FINC
Fibronectin

1

6

High-throughput

0.479

High

385952

P53
Cellular tumor antigen p53

1

8

Small-scale

0.479

High

414541

PTMA
Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]

1

4

Small-scale

0.479

High

444993

F16P1
Fructose-1,6-bisphosphatase 1

1

6

High-throughput

0.479

High

444994

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

14

High-throughput

0.479

High

444995

ARAF
Serine/threonine-protein kinase A-Raf

1

6

High-throughput

0.479

High

444999

ITA4
Integrin alpha-4

1

3

High-throughput

0.479

High

445001

EGR1
Early growth response protein 1

1

6

High-throughput

0.479

High

445005

CBL
E3 ubiquitin-protein ligase CBL

1

10

High-throughput

0.479

High

445008

SHC1
SHC-transforming protein 1

1

20

High-throughput

0.479

High

445014

EPS15
Epidermal growth factor receptor substrate 15

1

18

High-throughput

0.479

High

445015

CRK
Adapter molecule crk

1

20

High-throughput

0.479

High

445016

YAP1
Transcriptional coactivator YAP1

1

20

High-throughput

0.479

High

445023

TERA
Transitional endoplasmic reticulum ATPase

1

6

High-throughput

0.479

High

445025

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

13

High-throughput

0.479

High

445026

RBX1
E3 ubiquitin-protein ligase RBX1

1

1

High-throughput

0.479

High

445027

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.479

High

445030

ARF1
ADP-ribosylation factor 1

1

6

High-throughput

0.479

High

445031

ARF5
ADP-ribosylation factor 5

1

6

High-throughput

0.479

High

445034

EWS
RNA-binding protein EWS

1

1

High-throughput

0.479

High

445037

TFCP2
Alpha-globin transcription factor CP2

1

8

High-throughput

0.479

High

445038

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

20

High-throughput

0.479

High

445039

TRI26
Tripartite motif-containing protein 26

1

13

Small-scale

0.479

High

445044

DX39B
Spliceosome RNA helicase DDX39B

1

20

High-throughput

0.479

High

445047

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

20

High-throughput

0.479

High

445050

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

9

High-throughput

0.479

High

445051

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

18

High-throughput

0.479

High

445055

EZH2
Histone-lysine N-methyltransferase EZH2

1

14

High-throughput

0.479

High

445062

LARP7
La-related protein 7

1

16

High-throughput

0.479

High

445069

VIR
Protein virilizer homolog

1

5

High-throughput

0.479

High

445072

PRP8
Pre-mRNA-processing-splicing factor 8

1

11

High-throughput

0.479

High

445073

RICTR
Rapamycin-insensitive companion of mTOR

1

6

High-throughput

0.479

High

445074

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

7

High-throughput

0.479

High

445075

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

445076

MEPCE
7SK snRNA methylphosphate capping enzyme

1

15

High-throughput

0.479

High

445083

RBM45
RNA-binding protein 45

1

1

High-throughput

0.479

High

445087

RHG24
Rho GTPase-activating protein 24

1

6

High-throughput

0.479

High

445094

UBS3B
Ubiquitin-associated and SH3 domain-containing protein B

1

20

High-throughput

0.479

High

445095

HDAC2
Histone deacetylase 2

1

13

High-throughput

0.479

High

445096

TANK
TRAF family member-associated NF-kappa-B activator

1

2

High-throughput

0.479

High

445100

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

8

Small-scale

0.479

High

445101

AP2M1
AP-2 complex subunit mu

1

8

High-throughput

0.479

High

445102

MBD6
Methyl-CpG-binding domain protein 6

1

5

High-throughput

0.479

High

445103

RNF31
E3 ubiquitin-protein ligase RNF31

1

17

High-throughput

0.479

High

445108

NECD
Necdin

1

5

High-throughput

0.479

High

445113

ACE2
Angiotensin-converting enzyme 2

1

8

High-throughput

0.479

High

445114

TRIM7
E3 ubiquitin-protein ligase TRIM7

1

9

Small-scale

0.479

High

445118

RNF38
E3 ubiquitin-protein ligase RNF38

1

3

Small-scale

0.479

High

445120

CCDC8
Coiled-coil domain-containing protein 8

1

4

High-throughput

0.479

High

445125

NMRL1
NmrA-like family domain-containing protein 1

1

2

High-throughput

0.479

High

445127

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

15

High-throughput

0.479

High

445128

ANLN
Anillin

1

12

High-throughput

0.479

High

445134

MBD5
Methyl-CpG-binding domain protein 5

1

3

High-throughput

0.479

High

445135

HDAC6
Histone deacetylase 6

1

18

High-throughput

0.479

High

445137

ZRAN1
Ubiquitin thioesterase ZRANB1

1

14

High-throughput

0.479

High

445140

FZR1
Fizzy-related protein homolog

1

16

High-throughput

0.479

High

445142

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

19

Small-scale

0.479

High

445144

NEMO
NF-kappa-B essential modulator

1

8

Small-scale

0.479

High

57665

A2BDD9
AMOT protein

1

20

High-throughput

0.470

High

268375

BAF
Barrier-to-autointegration factor

1

0

Small-scale

0.458

High

305912

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

20

High-throughput

0.445

High

353619

IGHG1
Immunoglobulin heavy constant gamma 1

1

10

High-throughput

0.445

High

444996

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.445

High

445003

VCAM1
Vascular cell adhesion protein 1

1

5

High-throughput

0.445

High

445009

BMI1
Polycomb complex protein BMI-1

1

15

High-throughput

0.445

High

445024

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

20

High-throughput

0.445

High

445065

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

8

High-throughput

0.445

High

445089

RYBP
RING1 and YY1-binding protein

1

2

High-throughput

0.445

High

445116

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

20

High-throughput

0.445

High

445119

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

20

High-throughput

0.445

High

445004

EFNA1
Ephrin-A1

1

20

High-throughput

0.437

High

445019

EFNA3
Ephrin-A3

1

20

High-throughput

0.437

High

445020

EFNA4
Ephrin-A4

1

20

High-throughput

0.437

High

445064

EMC4
ER membrane protein complex subunit 4

1

4

High-throughput

0.437

High

445066

RC3H1
Roquin-1

1

12

High-throughput

0.437

High

445098

PTPR2
Receptor-type tyrosine-protein phosphatase N2

1

3

High-throughput

0.437

High

445106

DIRA2
GTP-binding protein Di-Ras2

1

3

Small-scale

0.437

High

445117

DDX24
ATP-dependent RNA helicase DDX24

1

20

High-throughput

0.437

High

445124

RC3H2
Roquin-2

1

19

High-throughput

0.437

High

445136

KS6B2
Ribosomal protein S6 kinase beta-2

1

8

High-throughput

0.437

High

445141

AAR2
Protein AAR2 homolog

1

6

High-throughput

0.437

High

900

SIM26
Small integral membrane protein 26

1

5

High-throughput

0.407

High

445045

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

7

High-throughput

0.407

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024