Interactor 1: CASPA (Q9I9L7)
Caspase a (EC 3.4.22.36) [Cleaved into: Caspase a subunit p20; Caspase a subunit p10]
Gene: CASPA

Interactor 2: ASC (Q9I9N6)
Apoptosis-associated speck-like protein containing a CARD (PYD and CARD domain-containing protein)
Gene: pycard

Species: Danio rerio

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 12464617
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PYRIN~PYRIN
Common GO terms GO:0002221 - pattern recognition receptor signaling pathway
GO:0005737 - cytoplasm
GO:0032090 - Pyrin domain binding
GO:0032731 - positive regulation of interleukin-1 beta production
GO:0045087 - innate immune response
and 4 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 383
Dr

1 203
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024