Interactor 1: NGDN (Q8NEJ9)
Neuroguidin (Centromere accumulated nuclear protein 1) (CANu1) (EIF4E-binding protein)
Gene: NGDN

Interactor 2: AATF (Q9NY61)
Protein AATF (Apoptosis-antagonizing transcription factor) (Rb-binding protein Che-1)
Gene: AATF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.752

The method score is based on:

Property Details
Experiments 25416956, 30021884, 33961781, 37071682, 35575683, 35271311, 31363146, 40437099
Identification Methods two hybrid, proximity labelling technology, affinity chromatography technology, cross-linking study, validated two hybrid, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0032040 - small-subunit processome
GO:0042274 - ribosomal small subunit biogenesis
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 315
Hs

1 560
+ Dm
+ At
+ At
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025