HitPredict

Interactor 1: DDX3X (O00571)
ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (CAP-Rf) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (DBX) (Helicase-like protein 2) (HLP2)
Gene: DDX3X

Interactor 2: PRC2A (P48634)
Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2)
Gene: PRRC2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030154 - cell differentiation and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 662 Hs			1 2157
+	Hs
		134074 DDX3X_HUMAN (1-662): 0: 614: 100.00		PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60
+	Hs
		134116 DDX3X_HUMAN (1-662): 0: 614: 100.00		ANKH1_HUMAN (88-992): 9.48e-35: 148: 14.15
+	Hs
		134254 DDX3X_HUMAN (1-662): 0: 614: 100.00		SRRM2_HUMAN (238-2035): 2.29e-34: 147: 9.83
+	Hs
		134264 DDX3X_HUMAN (1-662): 0: 614: 100.00		PRC2C_HUMAN (33-1884): 4.13e-12: 74.4: 11.13
+	Hs
		134175 DDX3X_HUMAN (1-662): 0: 614: 100.00		CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78
+	Hs
		571636 DDX5_HUMAN (90-658): 2.78e-160: 476: 35.70		SRRM2_HUMAN (238-2035): 2.29e-34: 147: 9.83
+	Hs
		571557 DDX5_HUMAN (90-658): 2.78e-160: 476: 35.70		CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78
+	Ce
		1341548 Q9N3F4_CAEEL (105-651): 3.6e-159: 474: 51.73		Q9U3S5_CAEEL (342-847): 9.71e-09: 63.1: 18.74
+	Ce
		247907 Q95XY1_CAEEL (105-651): 5.4e-158: 471: 51.64		O62011_CAEEL (342-847): 7.87e-09: 63.1: 18.55
+	Hs
		1271630 DDX17_HUMAN (122-661): 2.1e-152: 459: 36.38		CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78