Protein: SRP19
Signal recognition particle 19 kDa protein (SRP19)

Gene: SRP19
Organism: Homo sapiens
Interactions: 233
UniProt ID: P09132

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005730 - nucleolus
GO:0005786 - signal recognition particle, endoplasmic reticulum targeting
GO:0005829 - cytosol
GO:0006613 - cotranslational protein targeting to membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

479486

SRP68
Signal recognition particle subunit SRP68

4

1

Small-scale

0.702

High

479363

SRP54
Signal recognition particle subunit SRP54

1

3

High-throughput

0.691

High

479351

SRP09
Signal recognition particle 9 kDa protein

3

1

High-throughput

0.675

High

303389

SRP72
Signal recognition particle subunit SRP72

2

1

High-throughput

0.628

High

479425

LARP7
La-related protein 7

2

3

High-throughput

0.611

High

479440

LYRIC
Protein LYRIC

2

0

High-throughput

0.602

High

479309

SRP19
Signal recognition particle 19 kDa protein

1

0

High-throughput

0.586

High

133925

IPO5
Importin-5

1

1

Small-scale

0.561

High

189091

IPO8
Importin-8

1

2

Small-scale

0.561

High

334664

IPO7
Importin-7

1

3

Small-scale

0.561

High

479456

TNPO1
Transportin-1

1

3

Small-scale

0.561

High

395354

ESR1
Estrogen receptor

2

0

High-throughput

0.547

High

479310

FGFR1
Fibroblast growth factor receptor 1

2

0

High-throughput

0.547

High

295077

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

1

High-throughput

0.536

High

345281

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.536

High

468973

SRPRA
Signal recognition particle receptor subunit alpha

1

3

High-throughput

0.536

High

479311

PABP1
Polyadenylate-binding protein 1

1

1

High-throughput

0.536

High

479313

EF2
Elongation factor 2

1

1

High-throughput

0.536

High

479320

NUCL
Nucleolin

1

1

High-throughput

0.536

High

479333

SRP14
Signal recognition particle 14 kDa protein

1

1

High-throughput

0.536

High

479338

RS27
Small ribosomal subunit protein eS27

1

1

High-throughput

0.536

High

479349

PRC2A
Protein PRRC2A

1

1

High-throughput

0.536

High

479356

RRP1
Ribosomal RNA processing protein 1 homolog A

1

1

High-throughput

0.536

High

479361

IF4A1
Eukaryotic initiation factor 4A-I

1

1

High-throughput

0.536

High

479379

RS11
Small ribosomal subunit protein uS17

1

1

High-throughput

0.536

High

479406

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

1

High-throughput

0.536

High

479408

DHX9
ATP-dependent RNA helicase A

1

2

High-throughput

0.536

High

479415

PWP1
Periodic tryptophan protein 1 homolog

1

1

High-throughput

0.536

High

479416

NOG2
Nucleolar GTP-binding protein 2

1

2

High-throughput

0.536

High

479419

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

1

High-throughput

0.536

High

479420

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

1

High-throughput

0.536

High

479426

PDCD4
Programmed cell death protein 4

1

1

High-throughput

0.536

High

479429

DHX57
Putative ATP-dependent RNA helicase DHX57

1

2

High-throughput

0.536

High

479430

LARP1
La-related protein 1

1

2

High-throughput

0.536

High

479432

LARP4
La-related protein 4

1

2

High-throughput

0.536

High

479433

RS27L
Ribosomal protein eS27-like

1

1

High-throughput

0.536

High

479435

DHX30
ATP-dependent RNA helicase DHX30

1

2

High-throughput

0.536

High

479441

KTN1
Kinectin

1

1

High-throughput

0.536

High

479447

DDX54
ATP-dependent RNA helicase DDX54

1

1

High-throughput

0.536

High

479453

PSPC1
Paraspeckle component 1

1

1

High-throughput

0.536

High

479469

GNL3
Guanine nucleotide-binding protein-like 3

1

2

High-throughput

0.536

High

479471

GTPB4
GTP-binding protein 4

1

1

High-throughput

0.536

High

479473

LSG1
Large subunit GTPase 1 homolog

1

2

High-throughput

0.536

High

479477

STAU2
Double-stranded RNA-binding protein Staufen homolog 2

1

1

High-throughput

0.536

High

479483

RRBP1
Ribosome-binding protein 1

1

1

High-throughput

0.536

High

479494

DRG1
Developmentally-regulated GTP-binding protein 1

1

1

High-throughput

0.536

High

479499

PRC2C
Protein PRRC2C

1

1

High-throughput

0.536

High

182895

NKRF
NF-kappa-B-repressing factor

1

0

High-throughput

0.513

High

187866

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

0

High-throughput

0.513

High

258413

EDF1
Endothelial differentiation-related factor 1

1

0

High-throughput

0.513

High

295278

EIF3J
Eukaryotic translation initiation factor 3 subunit J

1

0

High-throughput

0.513

High

319322

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.513

High

361072

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.513

High

417221

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.513

High

428039

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.513

High

428267

RLA2
Large ribosomal subunit protein P2

1

0

High-throughput

0.513

High

428573

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.513

High

446568

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

475242

RS17
Small ribosomal subunit protein eS17

1

0

High-throughput

0.513

High

476534

RSSA
Small ribosomal subunit protein uS2

1

0

High-throughput

0.513

High

479315

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.513

High

479317

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.513

High

479318

RL7
Large ribosomal subunit protein uL30

1

0

High-throughput

0.513

High

479319

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.513

High

479321

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

0

High-throughput

0.513

High

479322

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.513

High

479323

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.513

High

479324

DDX6
Probable ATP-dependent RNA helicase DDX6

1

0

High-throughput

0.513

High

479326

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.513

High

479328

RL12
Large ribosomal subunit protein uL11

1

0

High-throughput

0.513

High

479329

RL9
Large ribosomal subunit protein uL6

1

0

High-throughput

0.513

High

479331

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.513

High

479332

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.513

High

479334

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.513

High

479335

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.513

High

479336

RL13A
Large ribosomal subunit protein uL13

1

0

High-throughput

0.513

High

479337

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

0

High-throughput

0.513

High

479339

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.513

High

479340

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.513

High

479341

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.513

High

479342

RL21
Large ribosomal subunit protein eL21

1

0

High-throughput

0.513

High

479343

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.513

High

479344

RS9
Small ribosomal subunit protein uS4

1

0

High-throughput

0.513

High

479345

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.513

High

479346

RS10
Small ribosomal subunit protein eS10

1

0

High-throughput

0.513

High

479347

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

479348

RL29
Large ribosomal subunit protein eL29

1

0

High-throughput

0.513

High

479350

RL34
Large ribosomal subunit protein eL34

1

0

High-throughput

0.513

High

479353

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.513

High

479354

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

0

High-throughput

0.513

High

479357

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.513

High

479358

SC61G
Protein transport protein Sec61 subunit gamma

1

0

High-throughput

0.513

High

479359

EIF3E
Eukaryotic translation initiation factor 3 subunit E

1

0

High-throughput

0.513

High

479360

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.513

High

479362

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.513

High

479364

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.513

High

479366

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.513

High

479367

RL27
Large ribosomal subunit protein eL27

1

0

High-throughput

0.513

High

479368

RL37A
Large ribosomal subunit protein eL43

1

0

High-throughput

0.513

High

479369

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

0

High-throughput

0.513

High

479370

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.513

High

479371

RS8
Small ribosomal subunit protein eS8

1

0

High-throughput

0.513

High

479372

RS15A
Small ribosomal subunit protein uS8

1

0

High-throughput

0.513

High

479373

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

479374

RS14
Small ribosomal subunit protein uS11

1

0

High-throughput

0.513

High

479375

RS23
Small ribosomal subunit protein uS12

1

0

High-throughput

0.513

High

479376

RS18
Small ribosomal subunit protein uS13

1

0

High-throughput

0.513

High

479377

RS29
Small ribosomal subunit protein uS14

1

0

High-throughput

0.513

High

479378

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.513

High

479380

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.513

High

479381

RS4X
Small ribosomal subunit protein eS4, X isoform

1

0

High-throughput

0.513

High

479382

RL23A
Large ribosomal subunit protein uL23

1

0

High-throughput

0.513

High

479383

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.513

High

479384

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.513

High

479385

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.513

High

479386

RS25
Small ribosomal subunit protein eS25

1

0

High-throughput

0.513

High

479387

RS26
Small ribosomal subunit protein eS26

1

0

High-throughput

0.513

High

479388

RS28
Small ribosomal subunit protein eS28

1

0

High-throughput

0.513

High

479389

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.513

High

479390

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.513

High

479391

RL10A
Large ribosomal subunit protein uL1

1

0

High-throughput

0.513

High

479392

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.513

High

479394

RL8
Large ribosomal subunit protein uL2

1

0

High-throughput

0.513

High

479395

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.513

High

479396

RS21
Small ribosomal subunit protein eS21

1

0

High-throughput

0.513

High

479397

RACK1
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.513

High

479399

RL24
Large ribosomal subunit protein eL24

1

0

High-throughput

0.513

High

479400

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.513

High

479403

XPC
DNA repair protein complementing XP-C cells

1

0

High-throughput

0.513

High

479404

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.513

High

479407

RL18
Large ribosomal subunit protein eL18

1

0

High-throughput

0.513

High

479410

ILF2
Interleukin enhancer-binding factor 2

1

0

High-throughput

0.513

High

479412

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

0

High-throughput

0.513

High

479414

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.513

High

479417

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

0

High-throughput

0.513

High

479418

CAPR1
Caprin-1

1

0

High-throughput

0.513

High

479422

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

1

0

High-throughput

0.513

High

479424

TSR1
Pre-rRNA-processing protein TSR1 homolog

1

0

High-throughput

0.513

High

479427

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.513

High

479434

SND1
Staphylococcal nuclease domain-containing protein 1

1

0

High-throughput

0.513

High

479436

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

0

High-throughput

0.513

High

479437

TRM1L
tRNA

1

0

High-throughput

0.513

High

479438

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.513

High

479444

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.513

High

479445

BBS1
BBSome complex member BBS1

1

0

High-throughput

0.513

High

479448

BRX1
Ribosome biogenesis protein BRX1 homolog

1

0

High-throughput

0.513

High

479449

DOK4
Docking protein 4

1

0

High-throughput

0.513

High

479450

ZC3HF
Zinc finger CCCH domain-containing protein 15

1

0

High-throughput

0.513

High

479454

H1X
Histone H1.10

1

0

High-throughput

0.513

High

479457

RL36L
Ribosomal protein eL42-like

1

0

High-throughput

0.513

High

479458

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

479459

RNF25
E3 ubiquitin-protein ligase RNF25

1

0

High-throughput

0.513

High

479460

CC124
Coiled-coil domain-containing protein 124

1

0

High-throughput

0.513

High

479461

RRP36
Ribosomal RNA processing protein 36 homolog

1

0

High-throughput

0.513

High

479462

LTV1
Protein LTV1 homolog

1

0

High-throughput

0.513

High

479465

TREF1
Transcriptional-regulating factor 1

1

0

High-throughput

0.513

High

479466

SRPK1
SRSF protein kinase 1

1

0

High-throughput

0.513

High

479467

POP1
Ribonucleases P/MRP protein subunit POP1

1

0

High-throughput

0.513

High

479468

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

0

High-throughput

0.513

High

479475

E41L5
Band 4.1-like protein 5

1

0

High-throughput

0.513

High

479479

SDA1
Protein SDA1 homolog

1

0

High-throughput

0.513

High

479480

LYAR
Cell growth-regulating nucleolar protein

1

0

High-throughput

0.513

High

479481

TEX10
Testis-expressed protein 10

1

0

High-throughput

0.513

High

479484

EIF3K
Eukaryotic translation initiation factor 3 subunit K

1

0

High-throughput

0.513

High

479487

NOB1
RNA-binding protein NOB1

1

0

High-throughput

0.513

High

479488

G3BP2
Ras GTPase-activating protein-binding protein 2

1

0

High-throughput

0.513

High

479490

DIM1
Dimethyladenosine transferase

1

0

High-throughput

0.513

High

479491

RL26L
Ribosomal protein uL24-like

1

0

High-throughput

0.513

High

479492

PA2G4
Proliferation-associated protein 2G4

1

0

High-throughput

0.513

High

479493

EIF3L
Eukaryotic translation initiation factor 3 subunit L

1

0

High-throughput

0.513

High

479496

NOP16
Nucleolar protein 16

1

0

High-throughput

0.513

High

479497

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.513

High

479498

LAS1L
Ribosomal biogenesis protein LAS1L

1

0

High-throughput

0.513

High

479500

SRPRB
Signal recognition particle receptor subunit beta

1

0

High-throughput

0.513

High

421353

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

172419

XPO1
Exportin-1

1

3

High-throughput

0.479

High

400158

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

479325

RL13
Large ribosomal subunit protein eL13

1

1

High-throughput

0.479

High

479365

RS3A
Small ribosomal subunit protein eS1

1

1

High-throughput

0.479

High

479405

RL6
Large ribosomal subunit protein eL6

1

1

High-throughput

0.479

High

479421

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

479501

RBM8A
RNA-binding protein 8A

1

1

High-throughput

0.479

High

240548

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

347483

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

479393

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.458

High

479401

VIGLN
Vigilin

1

0

High-throughput

0.458

High

479402

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

High-throughput

0.458

High

479411

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

479423

SMN
Survival motor neuron protein

1

0

Small-scale

0.458

High

479455

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

479472

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

0

High-throughput

0.458

High

479485

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

94406

D6RAT0
Small ribosomal subunit protein eS1

1

1

High-throughput

0.445

High

344070

PTBP3
Polypyrimidine tract-binding protein 3

1

1

High-throughput

0.445

High

479442

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

Small-scale

0.438

High

315040

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.437

High

479316

KCRS
Creatine kinase S-type, mitochondrial

1

1

High-throughput

0.437

High

479398

NOMO3
BOS complex subunit NOMO3

1

1

High-throughput

0.437

High

250967

PRP17
Pre-mRNA-processing factor 17

1

0

High-throughput

0.426

High

107254

F8VR69
Ribosomal protein L6

1

1

High-throughput

0.407

High

116372

H3BUK8
Large ribosomal subunit protein eL13

1

1

High-throughput

0.407

High

479312

KCRU
Creatine kinase U-type, mitochondrial

1

1

High-throughput

0.407

High

479428

NOMO2
BOS complex subunit NOMO2

1

1

High-throughput

0.407

High

479352

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.391

High

191517

MAGB2
Melanoma-associated antigen B2

2

0

High-throughput

0.328

High

479413

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

2

0

High-throughput

0.300

High

370141

CYTN
Cystatin-SN

1

0

High-throughput

0.279

Low

479314

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.279

Low

479355

FCGRN
IgG receptor FcRn large subunit p51

1

0

High-throughput

0.279

Low

479409

ABD18
Protein ABHD18

1

0

High-throughput

0.279

Low

479439

MILR1
Allergin-1

1

0

High-throughput

0.279

Low

479446

NEUA
N-acylneuraminate cytidylyltransferase

1

0

High-throughput

0.279

Low

479451

ANR49
Ankyrin repeat domain-containing protein 49

1

0

High-throughput

0.279

Low

479452

ATRIP
ATR-interacting protein

1

0

High-throughput

0.279

Low

479464

SPB12
Serpin B12

1

0

High-throughput

0.279

Low

479476

NDF4
Neurogenic differentiation factor 4

1

0

High-throughput

0.279

Low

479478

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.279

Low

479489

SSRG
Translocon-associated protein subunit gamma

1

0

High-throughput

0.279

Low

479495

RT17
Small ribosomal subunit protein uS17m

1

0

High-throughput

0.279

Low

193955

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.249

Low

227328

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.249

Low

275604

NDUS2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

1

0

High-throughput

0.249

Low

324442

HEXI1
Protein HEXIM1

1

0

High-throughput

0.249

Low

479327

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

479330

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

479431

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

479443

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

0

High-throughput

0.249

Low

479470

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.249

Low

479474

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

479482

NDUAD
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

1

0

High-throughput

0.249

Low

97186

CK098
Uncharacterized protein C11orf98

1

0

High-throughput

0.232

Low

479463

MF14A
Hippocampus abundant transcript 1 protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025