Protein: IRF9
Interferon regulatory factor 9 (IRF-9) (IFN-alpha-responsive transcription factor subunit) (ISGF3 p48 subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF-3 gamma) (Transcriptional regulator ISGF3 subunit gamma)

Gene: IRF9
Organism: Homo sapiens
Interactions: 55
UniProt ID: Q00978

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0002376 - immune system process
GO:0003700 - DNA-binding transcription factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

855289

STAT2
Signal transducer and activator of transcription 2

14

20

Small-scale

0.983

High

786311

STAT1
Signal transducer and activator of transcription 1-alpha/beta

6

20

Small-scale

0.936

High

501032

IRF1
Interferon regulatory factor 1

3

15

Small-scale

0.849

High

962705

IRF9
Interferon regulatory factor 9

2

16

Small-scale

0.754

High

962718

IRF7
Interferon regulatory factor 7

2

16

Small-scale

0.754

High

344078

OAS1
2'-5'-oligoadenylate synthase 1

3

2

Small-scale

0.640

High

257600

ANR17
Ankyrin repeat domain-containing protein 17

2

3

High-throughput

0.628

High

962711

UB2R2
Ubiquitin-conjugating enzyme E2 R2

2

2

High-throughput

0.628

High

962714

ANKH1
Ankyrin repeat and KH domain-containing protein 1

2

3

High-throughput

0.628

High

962727

ARI1
E3 ubiquitin-protein ligase ARIH1

2

5

High-throughput

0.628

High

819582

INAR2
Interferon alpha/beta receptor 2

2

1

Small-scale

0.628

High

776649

STAT3
Signal transducer and activator of transcription 3

1

20

Small-scale

0.618

High

786475

STAT6
Signal transducer and activator of transcription 6

1

20

Small-scale

0.618

High

962709

IRF5
Interferon regulatory factor 5

1

17

Small-scale

0.618

High

962717

CBP
CREB-binding protein

1

17

Small-scale

0.618

High

962723

RAD18
E3 ubiquitin-protein ligase RAD18

2

0

High-throughput

0.602

High

397915

ISG15
Ubiquitin-like protein ISG15

2

10

Small-scale

0.584

High

456159

IFI6
Interferon alpha-inducible protein 6

2

1

Small-scale

0.584

High

117896

MYO1F
Unconventional myosin-If

1

3

High-throughput

0.541

High

211833

TLX3
T-cell leukemia homeobox protein 3

1

6

High-throughput

0.541

High

213319

TLX2
T-cell leukemia homeobox protein 2

1

9

High-throughput

0.541

High

308070

VENTX
Homeobox protein VENTX

1

4

High-throughput

0.541

High

540836

PO2F1
POU domain, class 2, transcription factor 1

1

4

High-throughput

0.541

High

678994

HXC9
Homeobox protein Hox-C9

1

9

High-throughput

0.541

High

962713

ARI3B
AT-rich interactive domain-containing protein 3B

1

7

High-throughput

0.541

High

962728

NR2E3
Photoreceptor-specific nuclear receptor

1

2

High-throughput

0.541

High

962708

FOXL1
Forkhead box protein L1

1

2

High-throughput

0.536

High

962725

MTUS1
Microtubule-associated tumor suppressor 1

1

4

High-throughput

0.536

High

962726

DD19B
ATP-dependent RNA helicase DDX19B

1

1

High-throughput

0.536

High

962729

HCFC2
Host cell factor 2

1

4

High-throughput

0.536

High

962715

DMRTD
Doublesex- and mab-3-related transcription factor C2

1

0

High-throughput

0.518

High

962719

DACH2
Dachshund homolog 2

1

0

High-throughput

0.518

High

962720

S10AD
Protein S100-A13

1

0

High-throughput

0.518

High

962722

GLP3L
Golgi phosphoprotein 3-like

1

0

High-throughput

0.513

High

587529

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

20

Small-scale

0.501

High

962707

TF65
Transcription factor p65

1

20

Small-scale

0.501

High

962712

I2BP1
Interferon regulatory factor 2-binding protein 1

1

3

Small-scale

0.481

High

364111

CXL10
C-X-C motif chemokine 10

1

10

Small-scale

0.479

High

386539

P53
Cellular tumor antigen p53

1

4

Small-scale

0.479

High

456223

IFIT2
Interferon-induced protein with tetratricopeptide repeats 2

1

7

Small-scale

0.479

High

456274

IFIT1
Interferon-induced protein with tetratricopeptide repeats 1

1

7

Small-scale

0.479

High

525903

IFM1
Interferon-induced transmembrane protein 1

1

1

Small-scale

0.479

High

690111

GBP1
Guanylate-binding protein 1

1

9

Small-scale

0.479

High

962706

IFM3
Interferon-induced transmembrane protein 3

1

1

Small-scale

0.479

High

962710

PWP1
Periodic tryptophan protein 1 homolog

1

1

High-throughput

0.479

High

962716

RSAD2
S-adenosylmethionine-dependent nucleotide dehydratase RSAD2

1

2

Small-scale

0.479

High

962724

EVL
Ena/VASP-like protein

1

1

Small-scale

0.479

High

962730

DNM3A
DNA

1

0

Small-scale

0.458

High

92419

E9PDP5
Ankyrin repeat and KH domain containing 1

1

3

High-throughput

0.445

High

667328

IL12A
Interleukin-12 subunit alpha

1

7

Small-scale

0.437

High

962721

CCL19
C-C motif chemokine 19

1

10

Small-scale

0.437

High

508460

TOP1
DNA topoisomerase 1

1

3

Small-scale

0.408

High

612840

FBLN1
Fibulin-1

2

0

High-throughput

0.328

High

157558

MGST3
Glutathione S-transferase 3, mitochondrial

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024