HitPredict

Interactor 1: DDX3X (O00571)
ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (CAP-Rf) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (DBX) (Helicase-like protein 2) (HLP2)
Gene: DDX3X

Interactor 2: PABP4 (Q13310)
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)
Gene: PABPC4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29395067, 34445801
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008143 - poly(A) binding and 1 others more... GO:0010494 - cytoplasmic stress granule
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 662 Hs			1 644
+	Hs
		133858 DDX3X_HUMAN (1-662): 0: 614: 100.00		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		133876 DDX3X_HUMAN (1-662): 0: 614: 100.00		NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82
+	Sc
		376580 DED1_YEAST (10-633): 3.96e-151: 452: 47.28		PABP_YEAST (2-290): 4.28e-66: 228: 30.07
+	Hs
		571302 DDX5_HUMAN (90-658): 2.78e-160: 476: 35.70		NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82
+	Mm
		857351 Q8BTS0_MOUSE (90-658): 2.61e-160: 476: 35.70		TIA1_MOUSE (4-86): 1.26e-12: 72: 30.12
+	Mm
		857323 DDX17_MOUSE (122-650): 1.24e-151: 455: 36.61		TIA1_MOUSE (4-86): 1.26e-12: 72: 30.12