Interactor 1: IRAK4 (Q8R4K2)
Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1)
Gene: IRAK4
Interactor 2: TIRAP (Q99JY1)
Toll/interleukin-1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (Adaptor protein Wyatt) (MyD88 adapter-like protein)
Gene: TIRAP
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.60 | 0.481 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19378012 |
| Identification Methods | protein complementation assay |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005737 - cytoplasm GO:0043123 - positive regulation of canonical NF-kappaB signal transduction GO:0045087 - innate immune response |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
