HitPredict

Interactor 1: CYLD (Q9NQC7)
Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)
Gene: CYLD

Interactor 2: TAB2 (Q9NYJ8)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2)
Gene: TAB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27591049, 31762063
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0008270 - zinc ion binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 956 Hs			1 693
+	Hs
		1234343 CYLD_HUMAN (1-956): 0: 1872: 100.00		TAB3_HUMAN (1-692): 2.31e-70: 245: 29.77
+	Hs
		980003 CYLD_HUMAN (1-956): 0: 1872: 100.00		IF4G1_HUMAN (71-521): 3.73e-21: 101: 8.28
+	Hs
		846878 CYLD_HUMAN (1-956): 0: 1872: 100.00		SMCA2_HUMAN (127-396): 1.06e-10: 67.5: 10.22
+	Hs
		847087 CYLD_HUMAN (1-956): 0: 1872: 100.00		SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81