Protein: PPCEL
Prolyl endopeptidase-like (EC 3.4.21.-) (Prolylendopeptidase-like)

Gene: PPCEL, PREPL
Organism: Homo sapiens
Interactions: 106
UniProt ID: Q4J6C6

Gene Ontology (top 5):
GO:0004252 - serine-type endopeptidase activity
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005794 - Golgi apparatus
GO:0005802 - trans-Golgi network

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

842211

THIM
3-ketoacyl-CoA thiolase, mitochondrial

3

1

High-throughput

0.667

High

1194833

RM41
Large ribosomal subunit protein mL41

3

0

High-throughput

0.634

High

1194827

RHG36
Rho GTPase-activating protein 36

4

2

High-throughput

0.630

High

132854

ODPX
Pyruvate dehydrogenase protein X component, mitochondrial

2

1

High-throughput

0.628

High

1194816

PPCEL
Prolyl endopeptidase-like

1

10

High-throughput

0.618

High

1194855

MTG2
Mitochondrial ribosome-associated GTPase 2

2

2

High-throughput

0.611

High

641790

SDHB
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

2

0

High-throughput

0.602

High

946494

YBEY
Endoribonuclease YbeY

2

0

High-throughput

0.602

High

1012515

RT34
Small ribosomal subunit protein mS34

2

0

High-throughput

0.602

High

1194830

RM10
Large ribosomal subunit protein uL10m

2

0

High-throughput

0.602

High

890702

RGS4
Regulator of G-protein signaling 4

2

0

High-throughput

0.595

High

882700

EFTU
Elongation factor Tu, mitochondrial

2

0

High-throughput

0.585

High

892579

DNLI3
DNA ligase 3

2

0

High-throughput

0.585

High

1194822

MRM1
rRNA methyltransferase 1, mitochondrial

2

0

High-throughput

0.585

High

1194858

UNKL
Putative E3 ubiquitin-protein ligase UNKL

2

0

High-throughput

0.585

High

279778

CISY
Citrate synthase, mitochondrial

2

2

High-throughput

0.584

High

1058051

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

2

1

High-throughput

0.584

High

1083626

MPPA
Mitochondrial-processing peptidase subunit alpha

2

2

High-throughput

0.584

High

183656

RT12
Small ribosomal subunit protein uS12m

2

1

High-throughput

0.571

High

1194837

ESR2
Estrogen receptor beta

2

2

High-throughput

0.552

High

1194848

TR61B
tRNA

2

0

High-throughput

0.547

High

690498

KAD4
Adenylate kinase 4, mitochondrial

1

1

High-throughput

0.536

High

1062821

QOR
Quinone oxidoreductase

1

1

High-throughput

0.536

High

1100608

DHRS2
Dehydrogenase/reductase SDR family member 2, mitochondrial

1

1

High-throughput

0.536

High

1194851

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

1

High-throughput

0.536

High

1194864

MRM2
rRNA methyltransferase 2, mitochondrial

1

1

High-throughput

0.536

High

1194865

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

1

1

High-throughput

0.536

High

1194845

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.530

High

635077

CAN3
Calpain-3

1

0

High-throughput

0.518

High

275303

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

1

0

High-throughput

0.513

High

278674

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

1

0

High-throughput

0.513

High

869170

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.513

High

914627

RM12
Large ribosomal subunit protein bL12m

1

0

High-throughput

0.513

High

1011279

RT25
Small ribosomal subunit protein mS25

1

0

High-throughput

0.513

High

1194824

FAHD1
Oxaloacetate tautomerase FAHD1, mitochondrial

1

0

High-throughput

0.513

High

1194826

LBX2
Transcription factor LBX2

1

0

High-throughput

0.513

High

1194829

RM21
Large ribosomal subunit protein bL21m

1

0

High-throughput

0.513

High

1194831

FABD
Malonyl-CoA-acyl carrier protein transacylase, mitochondrial

1

0

High-throughput

0.513

High

1194834

ETKMT
Electron transfer flavoprotein beta subunit lysine methyltransferase

1

0

High-throughput

0.513

High

1194842

RT24
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.513

High

1194846

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.513

High

1194859

BEX1
Protein BEX1

1

0

High-throughput

0.513

High

1194862

NPS3A
Protein NipSnap homolog 3A

1

0

High-throughput

0.513

High

1194866

RT17
Small ribosomal subunit protein uS17m

1

0

High-throughput

0.513

High

1194867

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

596134

H12
Histone H1.2

1

0

High-throughput

0.493

High

799916

COIL
Coilin

1

0

High-throughput

0.486

High

241867

PRKN
E3 ubiquitin-protein ligase parkin

1

6

High-throughput

0.479

High

281965

MPPB
Mitochondrial-processing peptidase subunit beta

1

2

High-throughput

0.479

High

287301

RF1M
Peptide chain release factor 1, mitochondrial

1

2

High-throughput

0.479

High

362045

AATM
Aspartate aminotransferase, mitochondrial

1

2

High-throughput

0.479

High

404103

GCR
Glucocorticoid receptor

1

2

High-throughput

0.479

High

471057

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.479

High

532634

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.479

High

652527

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

2

High-throughput

0.479

High

767057

PTN7
Tyrosine-protein phosphatase non-receptor type 7

1

3

High-throughput

0.479

High

828791

MDHM
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

856276

IF2M
Translation initiation factor IF-2, mitochondrial

1

2

High-throughput

0.479

High

1090419

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

3

High-throughput

0.479

High

1117744

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

4

High-throughput

0.479

High

1142557

PDK1
[Pyruvate dehydrogenase

1

1

High-throughput

0.479

High

1194817

SYAM
Alanine--tRNA ligase, mitochondrial

1

2

High-throughput

0.479

High

1194823

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

1

High-throughput

0.479

High

1194828

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

1194836

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

1194840

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

1

High-throughput

0.479

High

1194849

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

1

High-throughput

0.479

High

1194853

MTRFR
Mitochondrial translation release factor in rescue

1

2

High-throughput

0.479

High

1194863

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

2

High-throughput

0.479

High

1194868

RM11
Large ribosomal subunit protein uL11m

1

1

High-throughput

0.479

High

350883

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

361637

OTC
Ornithine transcarbamylase, mitochondrial

1

0

High-throughput

0.458

High

519125

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

559973

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.458

High

851904

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

1015485

RHOG
Rho-related GTP-binding protein RhoG

1

0

High-throughput

0.458

High

1048537

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1162352

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.458

High

1194820

SYRM
Probable arginine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1194832

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.458

High

1194838

MCUR1
Mitochondrial calcium uniporter regulator 1

1

0

High-throughput

0.458

High

1194839

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

1194841

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.458

High

1194844

EFGM
Elongation factor G, mitochondrial

1

0

High-throughput

0.458

High

1194847

MTG1
Mitochondrial ribosome-associated GTPase 1

1

0

High-throughput

0.458

High

1194850

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

1194852

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

1194856

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1194857

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

1194860

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

1194861

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

440586

FYN
Tyrosine-protein kinase Fyn

1

3

High-throughput

0.457

High

943953

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.457

High

528458

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

1

2

High-throughput

0.445

High

1194819

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.445

High

1194825

DR4L2
Dehydrogenase/reductase SDR family member 4-like 2

1

3

High-throughput

0.445

High

1194854

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.439

High

104693

F6VUV4
Dehydrogenase/reductase 4 like 2

1

2

High-throughput

0.437

High

653355

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

1165362

ODAPH
Odontogenesis associated phosphoprotein

2

0

High-throughput

0.328

High

1194835

GALD1
Glutamine amidotransferase-like class 1 domain-containing protein 1

2

0

High-throughput

0.328

High

60642

CI170
Uncharacterized protein encoded by LINC02872

1

0

High-throughput

0.279

Low

1194818

TEX30
Testis-expressed protein 30

1

0

High-throughput

0.279

Low

1194843

MET2A
tRNA N(3)-cytidine methyltransferase METTL2A

1

0

High-throughput

0.279

Low

1194821

TT39B
Tetratricopeptide repeat protein 39B

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025