Interactor 1: ITM2C (Q9NQX7)
Integral membrane protein 2C (Cerebral protein 14) (Transmembrane protein BRI3) [Cleaved into: CT-BRI3]
Gene: ITM2C

Interactor 2: ITM2B (Q9Y287)
Integral membrane protein 2B (Immature BRI2) (imBRI2) (Protein E25B) (Transmembrane protein BRI) (Bri) [Cleaved into: BRI2, membrane form (Mature BRI2) (mBRI2); BRI2 intracellular domain (BRI2 ICD); BRI2C, soluble form; Bri23 peptide (Bri2-23) (ABri23) (C-terminal peptide) (P23 peptide)]
Gene: ITM2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 0.90 0.546

The method score is based on:

Property Details
Experiments 34446781
Identification Methods anti bait coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains BRICHOS~BRICHOS
Common GO terms GO:0001540 - amyloid-beta binding
GO:0005524 - ATP binding
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0042985 - negative regulation of amyloid precursor protein biosynthetic process
and 1 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024