HitPredict

Interactor 1: SIR7 (Q9NRC8)
NAD-dependent protein deacetylase sirtuin-7 (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-7) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 7) (SIR2-like protein 7)
Gene: SIRT7

Interactor 2: TF3C3 (Q9Y5Q9)
General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma)
Gene: GTF3C3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22586326
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 400 Hs			1 886
+	Hs
		1236597 SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87		TF3C3_HUMAN (1-886): 1.1e-146: 457: 100.00
+	Hs
		1161417 SIR7_HUMAN (1-400): 0: 535: 100.00		SKI3_HUMAN (37-841): 9.67e-24: 110: 10.77
+	Hs
		1318157 SIR7_HUMAN (1-400): 0: 535: 100.00		CRNL1_HUMAN (306-760): 3.03e-16: 85.8: 8.77
+	Hs
		300269 SIR7_HUMAN (1-400): 0: 535: 100.00		PRP6_HUMAN (6-259): 5.65e-10: 65.4: 10.21
+	Hs
		1160941 SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87		CTR9_HUMAN (25-542): 4.17e-16: 85.4: 12.81
+	Hs
		300200 SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87		PRP6_HUMAN (6-259): 5.65e-10: 65.4: 10.21