HitPredict

Interactor 1: CLTR2 (Q9NS75)
Cysteinyl leukotriene receptor 2 (CysLTR2) (G-protein coupled receptor GPCR21) (hGPCR21) (G-protein coupled receptor HG57) (HPN321)
Gene: CYSLTR2

Interactor 2: CLTR1 (Q9Y271)
Cysteinyl leukotriene receptor 1 (CysLTR1) (Cysteinyl leukotriene D4 receptor) (LTD4 receptor) (G-protein coupled receptor HG55) (HMTMF81)
Gene: CYSLTR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.819

The method score is based on:

Property Details
Experiments 17693579, 21203429
Identification Methods fluorescent resonance energy transfer, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~7tm_1
Common GO terms GO:0001631 - cysteinyl leukotriene receptor activity
GO:0004974 - leukotriene receptor activity
GO:0005886 - plasma membrane
GO:0007218 - neuropeptide signaling pathway
GO:0008528 - G protein-coupled peptide receptor activity
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 346
Hs

1 337
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024