HitPredict

Interactor 1: IF2B1 (Q9NZI8)
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IMP1) (Coding region determinant-binding protein) (CRD-BP) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zipcode-binding protein 1) (ZBP-1)
Gene: IGF2BP1

Interactor 2: PUF60 (Q9UHX1)
Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (FUSE-binding protein-interacting repressor) (FBP-interacting repressor) (Ro-binding protein 1) (RoBP1) (Siah-binding protein 1) (Siah-BP1)
Gene: PUF60

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	17353931
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 577 Hs			1 559
+	Hs
		128332 IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85		PUF60_HUMAN (1-559): 2.1e-103: 324: 100.00
+	Hs
		128177 IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		1054631 IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		128159 IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85		ELAV2_HUMAN (223-553): 1.56e-45: 165: 14.80
+	Hs
		128270 IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85		PABP5_HUMAN (133-308): 3.43e-45: 165: 23.86
+	Hs
		1020343 IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00		ELAV2_HUMAN (223-553): 1.56e-45: 165: 14.80
+	Hs
		642802 IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00		ELAV4_HUMAN (16-210): 6.97e-20: 93.7: 16.92
+	Hs
		128256 IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85		CELF1_HUMAN (98-214): 1.29e-17: 87.5: 26.50
+	Hs
		1272119 IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00		CELF1_HUMAN (98-214): 1.29e-17: 87.5: 26.50
+	Hs
		311358 IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00		CELF2_HUMAN (116-203): 3.74e-17: 86.5: 31.82
+	Hs
		128165 IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85		PABP4_HUMAN (457-550): 1.89e-10: 65.7: 10.64
+	Hs
		128007 IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64
+	Hs
		1031481 IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00		PABP4_HUMAN (457-550): 1.89e-10: 65.7: 10.64
+	Hs
		516722 IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64
+	Xl
		251139 IF23A_XENLA (1-577): 1.61e-140: 421: 73.06		EPABA_XENLA (476-559): 3.12e-13: 74.6: 17.86
+	Hs
		1054332 PCBP2_HUMAN (407-575): 6.35e-44: 162: 27.43		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Zm
		8143 A0A1D6ELH4_MAIZE (3-574): 1.31e-58: 208: 12.40		A0A1D6ELH4_MAIZE (2-130): 8.57e-11: 66.9: 8.89
+	Hs
		1072148 PCBP2_HUMAN (407-575): 6.35e-44: 162: 27.43		CELF1_HUMAN (98-214): 1.29e-17: 87.5: 26.50
+	Hs
		516531 PCBP2_HUMAN (407-575): 6.35e-44: 162: 27.43		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64
+	Hs
		311359 IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84		CELF2_HUMAN (116-203): 3.74e-17: 86.5: 31.82