HitPredict

Interactor 1: IMA3 (O00629)
Importin subunit alpha-3 (Importin alpha Q1) (Qip1) (Karyopherin subunit alpha-4)
Gene: KPNA4

Interactor 2: RANB3 (Q9H6Z4)
Ran-binding protein 3 (RanBP3)
Gene: RANBP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	37219487
Identification Methods	unspecified method, phage display
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005643 - nuclear pore GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 521 Hs			1 567
+	Hs
		134978 IMA3_HUMAN (1-521): 1.57e-165: 480: 100.00		NUP50_HUMAN (90-510): 4.88e-46: 170: 12.97
+	Hs
		131527 IMA4_HUMAN (1-521): 2.77e-161: 469: 85.80		NUP50_HUMAN (90-510): 4.88e-46: 170: 12.97
+	Hs
		134921 IMA3_HUMAN (1-521): 1.57e-165: 480: 100.00		RGPD4_HUMAN (247-548): 7.02e-36: 146: 16.94
+	Hs
		63862 IMA3_HUMAN (1-521): 1.57e-165: 480: 100.00		RGPD3_HUMAN (246-548): 6.71e-35: 143: 16.03
+	Hs
		134854 IMA3_HUMAN (1-521): 1.57e-165: 480: 100.00		RBP2_HUMAN (248-564): 3.22e-33: 138: 17.52
+	At
		1280910 IMPA1_ARATH (1-521): 3.44e-158: 462: 43.72		NU50A_ARATH (79-536): 6.54e-41: 155: 14.50
+	At
		97810 IMPA2_ARATH (1-521): 1.4e-157: 461: 44.69		NU50A_ARATH (79-536): 6.54e-41: 155: 14.50
+	Hs
		134843 IMA3_HUMAN (1-521): 1.57e-165: 480: 100.00		RANG_HUMAN (355-549): 1.54e-34: 131: 17.73
+	At
		285384 IMPA4_ARATH (1-521): 2.9e-155: 455: 41.64		NU50A_ARATH (79-536): 6.54e-41: 155: 14.50
+	Hs
		131404 IMA4_HUMAN (1-521): 2.77e-161: 469: 85.80		RBP2_HUMAN (248-564): 3.22e-33: 138: 17.52
+	At
		1320502 IMPA6_ARATH (1-521): 2.38e-153: 450: 43.41		NU50A_ARATH (79-536): 6.54e-41: 155: 14.50
+	At
		138100 IMPA3_ARATH (1-521): 7.35e-152: 446: 43.55		NU50A_ARATH (79-536): 6.54e-41: 155: 14.50
+	Hs
		131396 IMA4_HUMAN (1-521): 2.77e-161: 469: 85.80		RANG_HUMAN (355-549): 1.54e-34: 131: 17.73
+	Hs
		853515 IMA1_HUMAN (1-521): 1.39e-145: 430: 49.62		NUP50_HUMAN (90-510): 4.88e-46: 170: 12.97
+	Hs
		1192291 Q7Z726_HUMAN (1-521): 1.97e-145: 429: 49.62		NUP50_HUMAN (90-510): 4.88e-46: 170: 12.97
+	Hs
		238747 IMA7_HUMAN (1-521): 3.56e-142: 421: 46.46		NUP50_HUMAN (90-510): 4.88e-46: 170: 12.97
+	Hs
		152769 IMA1_HUMAN (1-521): 1.39e-145: 430: 49.62		RGPD8_HUMAN (246-547): 9.23e-36: 145: 16.72
+	Hs
		853440 IMA1_HUMAN (1-521): 1.39e-145: 430: 49.62		RGPD5_HUMAN (246-548): 1.48e-35: 144: 16.35
+	Hs
		834693 IMA1_HUMAN (1-521): 1.39e-145: 430: 49.62		RBP2_HUMAN (248-564): 3.22e-33: 138: 17.52
+	Sc
		691660 IMA1_YEAST (2-521): 1.2e-140: 417: 44.90		NUP2_YEAST (120-512): 1.75e-28: 122: 14.25