HitPredict

Interactor 1: VPS18 (Q9P253)
Vacuolar protein sorting-associated protein 18 homolog (hVPS18)
Gene: VPS18

Interactor 2: PKHM1 (Q9Y4G2)
Pleckstrin homology domain-containing family M member 1 (PH domain-containing family M member 1) (162 kDa adapter protein) (AP162)
Gene: PLEKHM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	28325809, 33452816
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005764 - lysosome GO:0031902 - late endosome membrane GO:0046872 - metal ion binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 973 Hs			1 1056
+	Hs
		1329152 VPS11_HUMAN (339-903): 3.18e-113: 373: 16.28		PKHM1_HUMAN (1-1056): 0: 1398: 100.00
+	Hs
		833175 VPS41_HUMAN (58-892): 2.31e-107: 354: 14.17		PKHM1_HUMAN (1-1056): 0: 1398: 100.00
+	Hs
		1295100 VPS39_HUMAN (369-884): 1.37e-88: 304: 13.98		PKHM1_HUMAN (1-1056): 0: 1398: 100.00