HitPredict

Interactor 1: E2F3 (O00716)
Transcription factor E2F3 (E2F-3)
Gene: E2F3

Interactor 2: E2F1 (Q01094)
Transcription factor E2F1 (E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1) (Retinoblastoma-binding protein 3) (RBBP-3) (pRB-binding protein E2F-1)
Gene: E2F1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 24981860, 35140242
Identification Methods affinity chromatography technology, proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains E2F_TDP~E2F_TDP
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 - cis-regulatory region sequence-specific DNA binding
and 11 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 465
Hs

1 437
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Last updated: 15 Jul 2024