HitPredict

Interactor 1: NXT1 (Q9U757)
NTF2-related export protein
Gene: nxt-1

Interactor 2: NXF2 (Q9XVS8)
Nuclear RNA export factor 2
Gene: nxf-2

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.693

Property	Details
Experiments	19123269, 22123199, 18692475, unassigned701
Identification Methods	two hybrid, biochemical, x-ray crystallography, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016973 - poly(A)+ mRNA export from nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 137 Ce			1 405
+	Hs
		1342974 NXT2_HUMAN (3-137): 1.04e-48: 154: 29.50		NXF1_HUMAN (1-401): 1.17e-166: 482: 27.90
+	Hs
		1354351 NXT1_HUMAN (5-137): 6.65e-47: 150: 29.20		NXF1_HUMAN (1-401): 1.17e-166: 482: 27.90
+	Mm
		1113012 NXT2_MOUSE (3-137): 4.35e-48: 153: 28.78		NXF1_MOUSE (1-401): 7.08e-164: 475: 26.91
+	Hs
		1030533 G3BP1_HUMAN (1-137): 7.54e-41: 143: 20.00		NXF1_HUMAN (1-401): 1.17e-166: 482: 27.90
+	Mm
		1307776 NXT1_MOUSE (5-137): 9.24e-47: 149: 29.20		NXF1_MOUSE (1-401): 7.08e-164: 475: 26.91
+	Hs
		1326869 NXT2_HUMAN (3-137): 1.04e-48: 154: 29.50		NXF2_HUMAN (1-394): 9.49e-160: 465: 25.95
+	Hs
		1326878 NXT1_HUMAN (5-137): 6.65e-47: 150: 29.20		NXF2_HUMAN (1-394): 9.49e-160: 465: 25.95
+	Hs
		903854 NTF2_HUMAN (17-135): 2.36e-40: 132: 24.79		NXF1_HUMAN (1-401): 1.17e-166: 482: 27.90
+	Ce
		1353757 NXT1_CAEEL (1-137): 2.46e-48: 153: 100.00		NXF1_CAEEL (1-400): 1.97e-129: 388: 44.91
+	Hs
		1330910 NXT2_HUMAN (3-137): 1.04e-48: 154: 29.50		NXF3_HUMAN (1-400): 3.82e-129: 383: 20.55
+	Hs
		1330913 NXT1_HUMAN (5-137): 6.65e-47: 150: 29.20		NXF3_HUMAN (1-400): 3.82e-129: 383: 20.55
+	Mm
		1113011 NXT2_MOUSE (3-137): 4.35e-48: 153: 28.78		Q8R499_MOUSE (3-400): 1.44e-122: 371: 21.66
+	Mm
		1246891 NXT1_MOUSE (5-137): 9.24e-47: 149: 29.20		Q8R499_MOUSE (3-400): 1.44e-122: 371: 21.66
+	Dm
		1353476 NXT1_DROME (8-137): 7.44e-42: 137: 29.23		NXF1_DROME (13-401): 1.54e-115: 353: 19.85
+	Mm
		1113010 NXT2_MOUSE (3-137): 4.35e-48: 153: 28.78		Q4ZGD9_MOUSE (16-401): 7.65e-102: 314: 20.05
+	Mm
		1119186 NXT1_MOUSE (5-137): 9.24e-47: 149: 29.20		Q4ZGD9_MOUSE (16-401): 7.65e-102: 314: 20.05
+	Dm
		1358683 NXT1_DROME (8-137): 7.44e-42: 137: 29.23		NXF2_DROME (20-402): 8.16e-92: 295: 23.06
+	Dm
		1214855 NXT1_DROME (8-137): 7.44e-42: 137: 29.23		Q8IQK4_DROME (12-399): 8.59e-88: 280: 21.39