HitPredict

Interactor 1: SAE1 (Q9UBE0)
SUMO-activating enzyme subunit 1 (Ubiquitin-like 1-activating enzyme E1A) [Cleaved into: SUMO-activating enzyme subunit 1, N-terminally processed]
Gene: SAE1

Interactor 2: HERC5 (Q9UII4)
E3 ISG15--protein ligase HERC5 (EC 2.3.2.-) (Cyclin-E-binding protein 1) (HECT domain and RCC1-like domain-containing protein 5)
Gene: HERC5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35671810
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 346 Hs			1 1024
+	Hs
		1252665 UBA3_HUMAN (28-337): 4.67e-82: 258: 17.68		HERC5_HUMAN (1-1024): 0: 1123: 100.00
+	Hs
		48142 UBA6_HUMAN (17-295): 1.69e-45: 168: 14.48		HERC5_HUMAN (1-1024): 0: 1123: 100.00
+	Hs
		607185 UBA1_HUMAN (4-242): 1.38e-39: 150: 14.73		HERC5_HUMAN (1-1024): 0: 1123: 100.00
+	Hs
		1039446 ULA1_HUMAN (239-343): 2.52e-17: 84.7: 28.18		HERC5_HUMAN (1-1024): 0: 1123: 100.00
+	Hs
		983260 SAE1_HUMAN (1-346): 1.12e-142: 409: 100.00		UBE3A_HUMAN (414-1024): 1.12e-172: 529: 25.37
+	Hs
		48079 UBA6_HUMAN (17-295): 1.69e-45: 168: 14.48		WWP2_HUMAN (599-1024): 1.14e-167: 516: 22.02
+	Hs
		48128 UBA6_HUMAN (17-295): 1.69e-45: 168: 14.48		ITCH_HUMAN (593-1024): 1.76e-165: 511: 24.22
+	Hs
		125155 UBA1_HUMAN (4-242): 1.38e-39: 150: 14.73		WWP2_HUMAN (599-1024): 1.14e-167: 516: 22.02
+	Hs
		607135 UBA1_HUMAN (4-242): 1.38e-39: 150: 14.73		ITCH_HUMAN (593-1024): 1.76e-165: 511: 24.22